Academic Journal
Mean arterial pressure estimated by brachial pulse wave analysis and comparison with currently used algorithms
العنوان: | Mean arterial pressure estimated by brachial pulse wave analysis and comparison with currently used algorithms |
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المؤلفون: | Grillo A., Salvi P., Furlanis G., Baldi C., Rovina M., Salvi L., Faini A., Bilo G., Fabris B., Carretta R., Benetos A., Parati G. |
المساهمون: | Grillo, A, Salvi, P, Furlanis, G, Baldi, C, Rovina, M, Salvi, L, Faini, A, Bilo, G, Fabris, B, Carretta, R, Benetos, A, Parati, G |
بيانات النشر: | Lippincott Williams & Wilkins US |
سنة النشر: | 2020 |
المجموعة: | Università degli Studi di Milano-Bicocca: BOA (Bicocca Open Archive) |
مصطلحات موضوعية: | adult, aged, algorithm, article, cohort analysi, controlled study, exercise test, female, human, hypertensive patient, major clinical study, male, mean arterial pressure, mental stre, pulse wave, systolic blood pressure, tonometry, waveform |
الوصف: | OBJECTIVE: Mean arterial pressure (MAP) is usually calculated by adding one-third of pulse pressure (PP) to DBP. This formula assumes that the average value of pulse waveform is constant in all individuals and coincides with 33.3% of PP amplitude (MAP = DBP + PP × 0.333). Other formulas were lately proposed to improve the MAP estimation, adding to DBP an established percentage of PP: MAP = DBP + PP × 0.40; MAP = DBP + PP × 0.412; MAP = DBP + PP × 0.333 + 5 mmHg. METHODS: The current study evaluated the integral of brachial pulse waveform recorded by applanation tonometry in 1526 patients belonging to three distinct cohorts: normotensive or hypertensive elderly, hypertensive adults, and normotensive adults. RESULTS: The percentage of PP to be added to DBP to obtain MAP was extremely variable among individuals, ranging from 23 to 58% (mean: 42.2 ± 5.5%), higher in women (42.9 ± 5.6%) than men (41.2 ± 5.1%, P < 0.001), lower in the elderly cohort (40.9 ± 5.3%) than in the general population cohort (42.8 ± 6.0%, P < 0.001) and in the hypertensive patients (42.4 ± 4.8%, P < 0.001). This percentage was significantly associated with DBP (β = 0.357, P < 0.001) and sex (β = 0.203, P < 0.001) and significantly increased after mental stress test in 19 healthy volunteers (from 39.9 ± 3.2 at baseline, to 43.0 ± 4.0, P < 0.0001). The average difference between MAP values estimated by formulas, compared with MAP assessed on the brachial tonometric curve, was (mean ± 1.96 × SD): -5.0 ± 6.7 mmHg when MAP = DBP + PP × 0333; -1.2 ± 6.1 mmHg when MAP = DBP + PP × 0.40; -0.6 ± 6.1 mmHg when MAP = DBP + PP × 0.412; -0.4 ± 6.7 mmHg when MAP = DBP + PP × 0.333 + 5. CONCLUSION: Due to high interindividual and intraindividual variability of pulse waveform, the estimation of MAP based on fixed formulas derived from SBP and DBP is unreliable. Conversely, a more accurate estimation of MAP should be based on the pulse waveform analysis. |
نوع الوثيقة: | article in journal/newspaper |
وصف الملف: | STAMPA |
اللغة: | English |
Relation: | info:eu-repo/semantics/altIdentifier/pmid/32694334; info:eu-repo/semantics/altIdentifier/wos/WOS:000588494400012; volume:38; issue:11; firstpage:2161; lastpage:2168; numberofpages:8; journal:JOURNAL OF HYPERTENSION; https://hdl.handle.net/10281/398415; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85092750111 |
DOI: | 10.1097/HJH.0000000000002564 |
الاتاحة: | https://hdl.handle.net/10281/398415 https://doi.org/10.1097/HJH.0000000000002564 |
Rights: | info:eu-repo/semantics/closedAccess |
رقم الانضمام: | edsbas.6892C7DD |
قاعدة البيانات: | BASE |
DOI: | 10.1097/HJH.0000000000002564 |
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