Academic Journal

Treatment and outcomes of patients with metastatic spinal cord compression: a double-center study

التفاصيل البيبلوغرافية
العنوان: Treatment and outcomes of patients with metastatic spinal cord compression: a double-center study
المؤلفون: Aycan, Abdurrahman, Aycan, N., Saglam, E., Tas, A., Karagoz Guzey, F., Eren, B., Celik, S., Akyol, Mehmet Edip, Kuyumcu, F.
سنة النشر: 2023
الوصف: OBJECTIVE: Spinal metastases may only affect the bone tissue and result in spinal instability or may additionally result in epidural compression, leading to neurological deficits. Surgery has emerged as a popular method in treating metastatic epidural spinal cord compression (MESCC) due to the advances in surgical techniques and instrumentation. In this study, we evaluated patients with MESCC regarding neurological status, pain status, and survival rates, and presented our experience managing MESCC. PATIENTS AND METHODS: Clinical and radiographic records of 53 patients diagnosed with MESCC between January 2011 and March 2017 were retrospectively evaluated. The study included patients with a pathological diagnosis of primary cancer, those who complained of spinal metastasis, and those who had indications of MESCC on Magnetic Resonance Imaging (MRI). Bone structure and spinal stability were evaluated using assessed Computed Tomography (CT), and metastatic spread was considered using assessed Positron Emission Tomography (PET) in suitable cases. For each patient, the presence of a tumor compressing the spinal cord, age, gender, preoperative, and postoperative American Spinal Injury Association scores (ASIA), Tokuhashi prognostic score (TPS), affected spinal segment, pathological diagnosis, preoperative, and postoperative Visual Analog Scale (VAS), the status of spinal stability, follow-up period, and complications were evaluated. RESULTS: Forty-five patients (82.2% of them were women) underwent surgery with a mean age of 58.29 ± 15.14 years. The most frequent type of primary tumor was multiple myeloma (33.9%), followed by lung (24.6%), gastric (7.5%), and prostate (5.7%). The most common site of metastasis was the thoracic region (43.4%), followed by lumbar (24.5%), multiple (24.5%), and cervical (5.7%). The analysis indicated that a significant difference was found between the survival rates of the TPS categories. CONCLUSIONS: Common symptoms of MESCC include spinal pain and neurological deficit below the level of ...
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: b5b86e03-6257-4bb8-9d92-306b9c33ef08; https://avesis.yyu.edu.tr/publication/details/b5b86e03-6257-4bb8-9d92-306b9c33ef08/oai
DOI: 10.26355/eurrev_202307_32968
الاتاحة: https://doi.org/10.26355/eurrev_202307_32968
https://avesis.yyu.edu.tr/publication/details/b5b86e03-6257-4bb8-9d92-306b9c33ef08/oai
Rights: info:eu-repo/semantics/closedAccess
رقم الانضمام: edsbas.6887CA4B
قاعدة البيانات: BASE
الوصف
DOI:10.26355/eurrev_202307_32968