Academic Journal
Risk factors for allergy documentation in electronic health record: A retrospective study in a tertiary health center in Switzerland.
| العنوان: | Risk factors for allergy documentation in electronic health record: A retrospective study in a tertiary health center in Switzerland. |
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| المؤلفون: | Ringwald, M., Moi, L., Wetzel, A., Comte, D., Muller, Y.D., Ribi, C. |
| المصدر: | Allergology international, vol. 73, no. 1, pp. 143-150 |
| سنة النشر: | 2024 |
| المجموعة: | Université de Lausanne (UNIL): Serval - Serveur académique lausannois |
| مصطلحات موضوعية: | Humans, Male, Female, Electronic Health Records, Retrospective Studies, Switzerland/epidemiology, Reproducibility of Results, Drug Hypersensitivity/diagnosis, Drug Hypersensitivity/epidemiology, Risk Factors, Monobactams, Documentation, Anaphylaxis/chemically induced, Anti-Bacterial Agents/adverse effects, Allergy, Drug hypersensitivity, Electronic health record (EHR), Medical informatics, Tertiary care center |
| الوصف: | Most hospitals use electronic health records (EHR) to warn health care professionals of drug hypersensitivity (DH) and other allergies. Indiscriminate recording of patient self-reported allergies may bloat the alert system, leading to unjustified avoidances and increases in health costs. The aim of our study was to analyze hypersensitivities documented in EHR of patients at Lausanne University Hospital (CHUV). We conducted a retrospective study on patients admitted at least 24 h to CHUV between 2011 and 2021. After ethical clearance, we obtained anonymized data. Because culprit allergen could be either manually recorded or selected through a list, data was harmonized using a reference allergy database before undergoing statistical analysis. Of 192,444 patients, 16% had at least one allergy referenced. DH constituted 60% of all allergy alerts, mainly beta-lactam antibiotics (BLA) (30%), NSAID (11%) and iodinated contrast media (ICM) (7%). Median age at first hospitalization and hospitalization length were higher in the allergy group. Female to male ratio was 2:1 in the allergic group. Reactions were limited to the skin in half of patients, and consistent with anaphylaxis in 6%. In those deemed allergic to BLA, culprit drug was specified in 19%, 'allergy to penicillin' otherwise. It was impossible to distinguish DH based on history alone or resulting from specialized work-up. Older age, longer hospital stays, and female sex increase the odds of in-patient allergy documentation. Regarding DH, BLA were referenced in 4% of inpatient records. Specific delabeling programs should be implemented to increase data reliability and patient safety. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/37455165; info:eu-repo/semantics/altIdentifier/eissn/1440-1592; info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_931C991F3DB52; https://serval.unil.ch/notice/serval:BIB_931C991F3DB5; https://serval.unil.ch/resource/serval:BIB_931C991F3DB5.P001/REF.pdf |
| DOI: | 10.1016/j.alit.2023.06.006 |
| الاتاحة: | https://serval.unil.ch/notice/serval:BIB_931C991F3DB5 https://doi.org/10.1016/j.alit.2023.06.006 https://serval.unil.ch/resource/serval:BIB_931C991F3DB5.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_931C991F3DB52 |
| Rights: | info:eu-repo/semantics/openAccess ; CC BY-NC-ND 4.0 ; https://creativecommons.org/licenses/by-nc-nd/4.0/ |
| رقم الانضمام: | edsbas.67BA6DBF |
| قاعدة البيانات: | BASE |
| DOI: | 10.1016/j.alit.2023.06.006 |
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