Academic Journal
Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit‐to‐Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid‐Lowering Treatment to Prevent Heart Attack Trial
| العنوان: | Effect of Chlorthalidone, Amlodipine, and Lisinopril on Visit‐to‐Visit Variability of Blood Pressure: Results From the Antihypertensive and Lipid‐Lowering Treatment to Prevent Heart Attack Trial |
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| المؤلفون: | Muntner, Paul, Levitan, Emily B., Lynch, Amy I., Simpson, Lara M., Whittle, Jeffrey, Davis, Barry R., Kostis, John B., Whelton, Paul K., Oparil, Suzanne |
| المساهمون: | National Heart, Lung, and Blood Institute of the National Institutes of Health, Pfizer, Inc. |
| المصدر: | The Journal of Clinical Hypertension ; volume 16, issue 5, page 323-330 ; ISSN 1524-6175 1751-7176 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2014 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Few randomized trials have compared visit‐to‐visit variability ( VVV ) of systolic blood pressure ( SBP ) across drug classes. The authors compared VVV of SBP among 24,004 participants randomized to chlorthalidone, amlodipine, or lisinopril in the Antihypertensive and Lipid‐Lowering Treatment to Prevent Heart Attack Trial ( ALLHAT ). VVV of SBP was calculated across 5 to 7 visits occurring 6 to 28 months following randomization. The standard deviation ( SD ) of SBP was 10.6 ( SD =5.0), 10.5 ( SD =4.9), and 12.2 ( SD =5.8) for participants randomized to chlorthalidone, amlodipine, and lisinopril, respectively. After multivariable adjustment including mean SBP across visits and compared with participants randomized to chlorthalidone, participants randomized to amlodipine had a 0.36 (standard error [ SE ]: 0.07) lower SD of SBP and participants randomized to lisinopril had a 0.77 ( SE =0.08) higher SD of SBP . Results were consistent using other VVV of SBP metrics. These data suggest chlorthalidone and amlodipine are associated with lower VVV of SBP than lisinopril. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1111/jch.12290 |
| الاتاحة: | http://dx.doi.org/10.1111/jch.12290 https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fjch.12290 https://onlinelibrary.wiley.com/doi/pdf/10.1111/jch.12290 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.6791B93C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1111/jch.12290 |
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