Academic Journal
Comparative analysis of serum and sebum concentration of super-bioavailable itraconazole 50 versus 65 mg in healthy adult volunteers
| العنوان: | Comparative analysis of serum and sebum concentration of super-bioavailable itraconazole 50 versus 65 mg in healthy adult volunteers |
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| المؤلفون: | Dhoot, Dhiraj S., Mahadkar, Namrata, Jain, Gaurav, Kesharwani, Prashant |
| المصدر: | International Journal of Research in Dermatology; Vol. 9 No. 1 (2023): January-February 2023; 59-60 ; 2455-4529 |
| بيانات النشر: | Medip Academy |
| سنة النشر: | 2022 |
| مصطلحات موضوعية: | Serum, Sebum, Super-bioavailable itraconazole, Dermatophytosis |
| الوصف: | Super-bioavailable itraconazole (SBITZ) is a new form of itraconazole which overcomes the pharmacokinetic issues of conventional itraconazole (CITZ). Currently two strengths are approved globally for SBITZ; 50 mg and 65 mg which exhibit greater bioavailability than CITZ and widely prescribed in systemic mycosis and dermatophytosis. Though both the strengths have proven to be bioequivalent with CITZ 100 mg but difference was reported in achieving therapeutic concentration of ITZ in patients. Secondly, skin kinetics study in terms of sebum concentration is lacking for both the strengths. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://www.ijord.com/index.php/ijord/article/view/1650/915; https://www.ijord.com/index.php/ijord/article/view/1650 |
| DOI: | 10.18203/issn.2455-4529.IntJResDermatol20223279 |
| الاتاحة: | https://www.ijord.com/index.php/ijord/article/view/1650 https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20223279 |
| Rights: | Copyright (c) 2022 International Journal of Research in Dermatology |
| رقم الانضمام: | edsbas.67814B1C |
| قاعدة البيانات: | BASE |
| DOI: | 10.18203/issn.2455-4529.IntJResDermatol20223279 |
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