التفاصيل البيبلوغرافية
| العنوان: |
Cyclodextrins as Drug Carrier Molecule: A Review |
| المؤلفون: |
ARUN RASHEED, ASHOK K., SRAVANTHI S. |
| المصدر: |
Scientia Pharmaceutica; Volume 76; Issue 4; Pages: 567-598 |
| بيانات النشر: |
Austrian Pharmaceutical Society |
| سنة النشر: |
2008 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
Cyclodextrins, Drug formulation, Drug delivery, Complexation, Novel delivery systems |
| الوصف: |
The cyclodextrins have a wide range of applications in different areas of drug delivery and pharmaceutical industry due to their complexation ability and other versatile characteristics. The most common pharmaceutical application of cyclodextrin is to enhance the solubility, stability, safety and bioavailability of drug molecules. The purpose of this review is to discuss and summarize some of the findings and applications of cyclodextrin (CD) and their derivatives in different areas of drug delivery. This article highlights the molecular structure, properties like complexation, solubility etc. of cyclodextrins and focuses on its use for parenteral, oral, ophthalmic and nasal drug delivery. Other routes including dermal, rectal, sublingual and pulmonary delivery are also briefly addressed. The objective of this contribution is to focus on the potential use of chemically modified cyclodextrins as high-performance drug carriers in drug delivery systems with emphasis on the more recent developments. Thus cyclodextrins, because of their continuing ability to find several novel applications in drug delivery, are expected to solve many problems associated with the delivery of different novel drugs through different delivery routes. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
https://dx.doi.org/10.3797/scipharm.0808-05 |
| DOI: |
10.3797/scipharm.0808-05 |
| الاتاحة: |
https://doi.org/10.3797/scipharm.0808-05 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.656BB1B6 |
| قاعدة البيانات: |
BASE |