Academic Journal
UTF1 Expression is Important for the Generation and Maintenance of Human iPSCs.
| العنوان: | UTF1 Expression is Important for the Generation and Maintenance of Human iPSCs. |
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| المؤلفون: | Raina, Khyati, Modak, Kirti, Premkumar, Chitra, Joshi, Gaurav, Palani, Dhavapriya, Nandy, Krittika, Sivamani, Yazhini, Velayudhan, Shaji R, Thummer, Rajkumar P |
| المصدر: | Stem Cell Rev Rep ; ISSN:2629-3277 |
| بيانات النشر: | Springer |
| سنة النشر: | 2025 |
| المجموعة: | PubMed Central (PMC) |
| مصطلحات موضوعية: | CRISPR/Cas9, Gene knockout, Human fibroblasts, Human induced pluripotent stem cells, Knockdown, Spontaneous differentiation, Undifferentiated embryonic cell transcription factor 1 |
| الوصف: | Undifferentiated embryonic cell transcription factor 1 (UTF1) is predominantly expressed in pluripotent stem cells and plays a vital role in embryonic development and pluripotency maintenance. Despite its established importance in murine models, the role of UTF1 on human induced pluripotent stem cells (iPSCs) has not been comprehensively studied. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://doi.org/10.1007/s12015-024-10836-x; https://pubmed.ncbi.nlm.nih.gov/39754619 |
| DOI: | 10.1007/s12015-024-10836-x |
| الاتاحة: | https://doi.org/10.1007/s12015-024-10836-x https://pubmed.ncbi.nlm.nih.gov/39754619 |
| Rights: | © 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature. |
| رقم الانضمام: | edsbas.64CBF2FC |
| قاعدة البيانات: | BASE |
| DOI: | 10.1007/s12015-024-10836-x |
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