Academic Journal
HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW Systematic Review and Meta-Analysis of the Association between b2-Adrenoceptor Polymorphisms and Asthma: A HuGE Review
| العنوان: | HUMAN GENOME EPIDEMIOLOGY (HuGE) REVIEW Systematic Review and Meta-Analysis of the Association between b2-Adrenoceptor Polymorphisms and Asthma: A HuGE Review |
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| المؤلفون: | Ammarin Thakkinstian, Mark Mcevoy, Cosetta Minelli, Peter Gibson, Bob Hancox, David Duffy, John Thompson, Ian Hall, Joel Kaufman, Ting-fan Leung, Peter Joseph Helms, Hakon Hakonarson, Eva Halpi, Ruth Navon, John Attia, Centre For Clinical Epidemiology |
| المساهمون: | The Pennsylvania State University CiteSeerX Archives |
| المصدر: | http://aje.oxfordjournals.org/content/early/2005/06/29/aje.kwi184.full.pdf. |
| سنة النشر: | 2005 |
| المجموعة: | CiteSeerX |
| الوصف: | A number of studies have investigated two common polymorphisms in the b2-adrenoceptor gene, Arg/Gly16 and Gln/Glu27, in relation to asthma susceptibility. The authors performed a meta-analysis of each polymorphism, as well as haplotype analysis, for adult and pediatric populations separately, using published data, supplemented by additional data requested from the original authors. Individual analysis detected no effect of Arg/Gly16 in adults but did suggest a recessive protective effect of Gly16 for children, with an odds ratio of 0.71 (95 % confidence interval (CI): 0.53, 0.96) compared with the other genotypes. Results for Gln/Glu27 in adults seem to indicate that hetero- |
| نوع الوثيقة: | text |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.9112; http://aje.oxfordjournals.org/content/early/2005/06/29/aje.kwi184.full.pdf |
| الاتاحة: | http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.603.9112 http://aje.oxfordjournals.org/content/early/2005/06/29/aje.kwi184.full.pdf |
| Rights: | Metadata may be used without restrictions as long as the oai identifier remains attached to it. |
| رقم الانضمام: | edsbas.6460E61F |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |