Academic Journal
Self-reported caffeine consumption miss-matched consumption measured by plasma levels of caffeine and its metabolites: results from two population-based studies.
| العنوان: | Self-reported caffeine consumption miss-matched consumption measured by plasma levels of caffeine and its metabolites: results from two population-based studies. |
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| المؤلفون: | Laaboub, Nermine, Ranjbar, Setareh, Strippoli, Marie-Pierre F, Marques-Vidal, Pedro, Estoppey-Younes, Sandrine, Ponte, Belen, Pruijm, Menno, Vogt, Bruno, Ansermot, Nicolas, Crettol, Séverine, Vandenberghe, Frederik, Vollenweider, Peter, Preisig, Martin, Bochud, Murielle, Eap, Chin B |
| المصدر: | Laaboub, Nermine; Ranjbar, Setareh; Strippoli, Marie-Pierre F; Marques-Vidal, Pedro; Estoppey-Younes, Sandrine; Ponte, Belen; Pruijm, Menno; Vogt, Bruno; Ansermot, Nicolas; Crettol, Séverine; Vandenberghe, Frederik; Vollenweider, Peter; , ; ; , (2024). Self-reported caffeine consumption miss-matched consumption measured by plasma levels of caffeine and its metabolites: results from two population-based studies. (In Press). European Journal of Nutrition Springer-Verlag 10.1007/s00394-024-03351-9 |
| بيانات النشر: | Springer-Verlag |
| سنة النشر: | 2024 |
| المجموعة: | BORIS (Bern Open Repository and Information System, University of Bern) |
| مصطلحات موضوعية: | 610 Medicine & health |
| الوصف: | IMPORTANCE AND OBJECTIVE Self-reported caffeine consumption has been widely used in research while it may be subject to bias. We sought to investigate the associations between self-reported caffeine consumption and plasma levels of caffeine and its two main metabolites (paraxanthine and theophylline) in the community. METHODS Data from two population-based studies (SKIPOGH1 and 2 (N = 1246) and CoLaus|PsyCoLaus (N = 4461)) conducted in Switzerland were used. Self-reported caffeine consumption was assessed using questionnaires. Plasma levels of caffeine and its metabolites were quantified by ultra-high performance liquid chromatography coupled to a tandem quadrupole mass spectrometer. RESULTS In both studies, mean log plasma levels of caffeine and its two metabolites were over 6.48 (plasma levels = 652 ng/ml) when no caffeine consumption was reported. Subsequently, nonlinear associations between log plasma levels and self-reported caffeine consumption were observed in SKIPOGH, with a change of the slope at 3-5 cups of espresso per day in SKIPOGH1 but not SKIPOGH2. In CoLaus|PsyCoLaus, increased daily consumption of caffeinated beverages was associated with increased log plasma levels with a change of the slope at 3 cups. In both studies, declared caffeine consumption higher than 3-5 cups per day was not associated with higher plasma levels of caffeine and its metabolites. CONCLUSION Self-reports of no or low caffeine consumption and consumption of more than 3-5 cups of coffee should be interpreted with caution, with possible under- or over-estimation. Quantifying plasma levels of caffeine and its metabolites may contribute to a better estimation of caffeine intake. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | https://boris.unibe.ch/196532/ |
| الاتاحة: | https://boris.unibe.ch/196532/1/s00394-024-03351-9.pdf https://boris.unibe.ch/196532/ |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.6455F15 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |