Academic Journal
A Novel Multi-Dimensional Clinical Response Index Dedicated to Improving Global Assessment of Pain in Patients with Persistent Spinal Pain Syndrome after Spinal Surgery, Based on a Real-Life Prospective Multicentric Study (PREDIBACK) and Machine Learning Techniques
| العنوان: | A Novel Multi-Dimensional Clinical Response Index Dedicated to Improving Global Assessment of Pain in Patients with Persistent Spinal Pain Syndrome after Spinal Surgery, Based on a Real-Life Prospective Multicentric Study (PREDIBACK) and Machine Learning Techniques |
|---|---|
| المؤلفون: | Rigoard, Philippe, Ounajim, Amine, Goudman, Lisa, Louis, Pierre-Yves, Slaoui, Yousri, Roulaud, Manuel, Naiditch, Nicolas, Bouche, Bénédicte, Page, Philippe, Lorgeoux, Bertille, Baron, Sandrine, Charrier, Elodie, Poupin, Laure, Rannou, Delphine, de Montgazon, Géraldine Brumauld, Roy-Moreau, Brigitte, Grimaud, Nelly, Adjali, Nihel, Nivole, Kevin, Many, Mathilde, David, Romain, Wood, Chantal, Rigoard, Raphael, Moens, Maarten, Billot, Maxime |
| المساهمون: | Predictive Research In Spine/Neurostimulation Management And Thoracic Innovation in Cardiac Surgery (PRISMATICS), Centre hospitalier universitaire de Poitiers = Poitiers University Hospital (CHU de Poitiers La Milétrie ), Photomécanique et analyse expérimentale en mécanique des solides Institut Pprime (PEM), Département Génie Mécanique et Systèmes Complexes Institut Pprime (Département GMSC), Institut Pprime UPR 3346 (PPrime Poitiers ), Université de Poitiers = University of Poitiers (UP)-École Nationale Supérieure de Mécanique et d’Aérotechnique Poitiers (ISAE-ENSMA)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers = University of Poitiers (UP)-École Nationale Supérieure de Mécanique et d’Aérotechnique Poitiers (ISAE-ENSMA)-Centre National de la Recherche Scientifique (CNRS)-Institut Pprime UPR 3346 (PPrime Poitiers ), Université de Poitiers = University of Poitiers (UP)-École Nationale Supérieure de Mécanique et d’Aérotechnique Poitiers (ISAE-ENSMA)-Centre National de la Recherche Scientifique (CNRS)-Université de Poitiers = University of Poitiers (UP)-École Nationale Supérieure de Mécanique et d’Aérotechnique Poitiers (ISAE-ENSMA)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de mathématiques et applications UMR 7348 (LMA Poitiers ), Université de Poitiers = University of Poitiers (UP)-Centre National de la Recherche Scientifique (CNRS), Universitair Ziekenhuis Brussel = University Hospital of Brussels (UZ Brussel), STIMULUS research group Vrije Universiteit Brussel, Belgium (STIMULUS), Vrije Universiteit Brussel Bruxelles (VUB), Institut de Mathématiques de Bourgogne Dijon (IMB), Université de Bourgogne (UB)-Centre National de la Recherche Scientifique (CNRS), Procédés Microbiologiques et Biotechnologiques (PMB), Procédés Alimentaires et Microbiologiques (PAM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Procédés Alimentaires et Microbiologiques Dijon (PAM), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté COMUE (UBFC)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Université Bourgogne Franche-Comté COMUE (UBFC), Procédés Alimentaires et Microbiologiques Dijon (PAM), Université de Bourgogne (UB)-Université Bourgogne Franche-Comté COMUE (UBFC)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), Centre régional d'étude et de traitement de la douleur : CHU de Poitiers (CETD), Hôpital Saint-Louis de La Rochelle (CH La Rochelle), Centre Hospitalier Georges Renon Niort (CH Georges Renon Niort), CEA Cadarache, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), MedtronicERP NM-3351Poitiers University Hospital, France |
| المصدر: | ISSN: 2077-0383 ; Journal of Clinical Medicine ; https://univ-poitiers.hal.science/hal-04392139 ; Journal of Clinical Medicine, 2021, 10 (21), pp.4910. ⟨10.3390/jcm10214910⟩ ; https://www.mdpi.com/2077-0383/10/21/4910. |
| بيانات النشر: | HAL CCSD MDPI |
| سنة النشر: | 2021 |
| المجموعة: | Université de Poitiers: Publications de nos chercheurs.ses (HAL) |
| مصطلحات موضوعية: | composite score, machine learning, PSPS, failed back surgery (FBSS), chronic pain, pain intensity, pain mapping, pain surface, functional capacity, psychological distress, Anxiety and depression, [SDV]Life Sciences [q-bio], [MATH.MATH-ST]Mathematics [math]/Statistics [math.ST] |
| الوصف: | International audience ; The multidimensionality of chronic pain forces us to look beyond isolated assessment such as pain intensity, which does not consider multiple key parameters, particularly in post-operative Persistent Spinal Pain Syndrome (PSPS-T2) patients. Our ambition was to produce a novel Multi-dimensional Clinical Response Index (MCRI), including not only pain intensity but also functional capacity, anxiety-depression, quality of life and quantitative pain mapping, the objective being to achieve instantaneous assessment using machine learning techniques. Two hundred PSPS-T2 patients were enrolled in the real-life observational prospective PREDIBACK study with 12-month follow-up and received various treatments. From a multitude of questionnaires/scores, specific items were combined, as exploratory factor analyses helped to create a single composite MCRI; using pairwise correlations between measurements, it appeared to more accurately represent all pain dimensions than any previous classical score. It represented the best compromise among all existing indexes, showing the highest sensitivity/specificity related to Patient Global Impression of Change (PGIC). Novel composite indexes could help to refine pain assessment by informing the physician’s perception of patient condition on the basis of objective and holistic metrics, and also by providing new insights regarding therapy efficacy/patient outcome assessments, before ultimately being adapted to other pathologies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/34768428; PUBMED: 34768428 |
| DOI: | 10.3390/jcm10214910 |
| الاتاحة: | https://univ-poitiers.hal.science/hal-04392139 https://univ-poitiers.hal.science/hal-04392139v1/document https://univ-poitiers.hal.science/hal-04392139v1/file/65-jcm-10-04910.pdf https://doi.org/10.3390/jcm10214910 |
| Rights: | http://creativecommons.org/licenses/by/ ; info:eu-repo/semantics/OpenAccess |
| رقم الانضمام: | edsbas.641A8D4A |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/jcm10214910 |
|---|