Academic Journal
The Relationship Between Invasive Nontyphoidal Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa
| العنوان: | The Relationship Between Invasive Nontyphoidal Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa |
|---|---|
| المؤلفون: | Park, Se Eun, Pak, Gi Deok, Aaby, Peter, Adu-Sarkodie, Yaw, Ali, Mohammad, Aseffa, Abraham, Biggs, Holly M., Bjerregaard-Andersen, Morten, Breiman, Robert F., Crump, John A., Cruz Espinoza, Ligia Maria, Eltayeb, Muna Ahmed, Gasmelseed, Nagla, Hertz, Julian T., Im, Justin, Jaeger, Anna, Parfait Kabore, Leon, von Kalckreuth, Vera, Keddy, Karen H., Konings, Frank, Krumkamp, Ralf, MacLennan, Calman A., Meyer, Christian G., Montgomery, Joel M., Ahmet Niang, Aissatou, Nichols, Chelsea, Olack, Beatrice, Panzner, Ursula, Park, Jin Kyung, Rabezanahary, Henintsoa, Rakotozandrindrainy, Raphael, Sampo, Emmanuel, Sarpong, Nimako, Schuett-Gerowitt, Heidi, Sooka, Arvinda, Soura, Abdramane Bassiahi, Sow, Amy Gassama, Tall, Adama, Teferi, Mekonnen, Yeshitela, Biruk, May, Juegen, Wierzba, Thomas F., Clemens, John D., Baker, Stephen, Marks, Florian |
| بيانات النشر: | OXFORD UNIV PRESS INC |
| سنة النشر: | 2016 |
| المجموعة: | Cologne University: KUPS |
| مصطلحات موضوعية: | ddc:no |
| الوصف: | Methods.aEuro integral Febrile patients received a blood culture and a malaria test. Isolated bacteria underwent antimicrobial susceptibility testing, and the association between iNTS disease and malaria was assessed. Results.aEuro integral A positive correlation between frequency proportions of malaria and iNTS was observed (P = .01; r = 0.70). Areas with higher burden of malaria exhibited higher odds of iNTS disease compared to other bacterial infections (odds ratio [OR], 4.89; 95% CI, 1.61-14.90; P = .005) than areas with lower malaria burden. Malaria parasite positivity was associated with iNTS disease (OR, 2.44; P = .031) and gram-positive bacteremias, particularly Staphylococcus aureus, exhibited a high proportion of coinfection with Plasmodium malaria. Salmonella Typhimurium and Salmonella Enteritidis were the predominant NTS serovars (53/73; 73%). Both moderate (OR, 6.05; P = .0001) and severe (OR, 14.62; P < .0001) anemia were associated with iNTS disease. Conclusions.aEuro integral A positive correlation between iNTS disease and malaria endemicity, and the association between Plasmodium parasite positivity and iNTS disease across sub-Saharan Africa, indicates the necessity to consider iNTS as a major cause of febrile illness in malaria-holoendemic areas. Prevention of iNTS disease through iNTS vaccines for areas of high malaria endemicity, targeting high-risk groups for Plasmodium parasitic infection, should be considered. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | Park, Se Eun, Pak, Gi Deok, Aaby, Peter orcid:0000-0001-8331-1389 , Adu-Sarkodie, Yaw, Ali, Mohammad, Aseffa, Abraham orcid:0000-0002-8028-1150 , Biggs, Holly M., Bjerregaard-Andersen, Morten, Breiman, Robert F., Crump, John A. orcid:0000-0002-4529-102X , Cruz Espinoza, Ligia Maria, Eltayeb, Muna Ahmed, Gasmelseed, Nagla, Hertz, Julian T., Im, Justin, Jaeger, Anna, Parfait Kabore, Leon, von Kalckreuth, Vera, Keddy, Karen H., Konings, Frank, Krumkamp, Ralf, MacLennan, Calman A., Meyer, Christian G., Montgomery, Joel M., Ahmet Niang, Aissatou, Nichols, Chelsea, Olack, Beatrice, Panzner, Ursula, Park, Jin Kyung, Rabezanahary, Henintsoa, Rakotozandrindrainy, Raphael, Sampo, Emmanuel, Sarpong, Nimako, Schuett-Gerowitt, Heidi, Sooka, Arvinda, Soura, Abdramane Bassiahi, Sow, Amy Gassama, Tall, Adama, Teferi, Mekonnen, Yeshitela, Biruk, May, Juegen, Wierzba, Thomas F., Clemens, John D., Baker, Stephen and Marks, Florian orcid:0000-0002-6043-7170 (2016). The Relationship Between Invasive Nontyphoidal Disease, Other Bacterial Bloodstream Infections, and Malaria in Sub-Saharan Africa. Clin. Infect. Dis., 62. S. S23 - 9. CARY: OXFORD UNIV PRESS INC. ISSN 1537-6591 |
| الاتاحة: | https://kups.ub.uni-koeln.de/28136/ |
| رقم الانضمام: | edsbas.63CA8F2B |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |