Academic Journal
Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study
| العنوان: | Local recurrence and metachronous multiple cancers after transoral nonrobotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study |
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| المؤلفون: | Ushiro, Koji, Watanabe, Yoshiki, Kishimoto, Yo, Kawai, Yoshitaka, Fujimura, Shintaro, Asato, Ryo, Tsujimura, Takashi, Hori, Ryusuke, Kumabe, Yohei, Yasuda, Kaori, Tamaki, Hisanobu, Iki, Takehiro, Kitani, Yoshiharu, Kurata, Keisuke, Kojima, Tsuyoshi, Takata, Kuniaki, Kada, Shinpei, Takebayashi, Shinji, Shinohara, Shogo, Hamaguchi, Kiyomi, Miyazaki, Masakazu, Ikenaga, Tadashi, Maetani, Toshiki, Harada, Hiroyuki, Haji, Tomoyuki, Omori, Koichi |
| المصدر: | Head & Neck ; volume 46, issue 1, page 118-128 ; ISSN 1043-3074 1097-0347 |
| بيانات النشر: | Wiley |
| سنة النشر: | 2023 |
| المجموعة: | Wiley Online Library (Open Access Articles via Crossref) |
| الوصف: | Background Late laryngopharyngeal cancers after transoral surgery include not only local recurrences but also metachronous multiple cancers. Methods We compared clinical information, surgical outcomes, and late laryngopharyngeal cancers in patients who underwent transoral nonrobotic surgery for laryngopharyngeal squamous cell carcinoma without lymph node metastases between 2015 and 2021 in a multicenter retrospective study. Results Four hundred and fifty‐seven patients were included. Positive surgical margins were found in 121 patients (26.5%). Twenty‐two patients (4.8%) received additional treatment. Positive horizontal margins of invasive carcinoma ( p = 0.003) and positive horizontal margins of carcinoma in situ only ( p = 0.032) were independent risk factors for local recurrence, and prior radiotherapy ( p = 0.001) for metachronous multiple cancers. Local control was significantly worse without additional treatment ( p = 0.049), but there was no significant difference in survival. Conclusions Patients with positive margins had an increased frequency of local recurrence, but salvage therapy was effective. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1002/hed.27564 |
| الاتاحة: | http://dx.doi.org/10.1002/hed.27564 https://onlinelibrary.wiley.com/doi/pdf/10.1002/hed.27564 |
| Rights: | http://onlinelibrary.wiley.com/termsAndConditions#vor |
| رقم الانضمام: | edsbas.62BD4513 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/hed.27564 |
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