التفاصيل البيبلوغرافية
| العنوان: |
Mtk is expressed at low baseline levels without infection and is highly induced with infection. |
| المؤلفون: |
Jessamyn I. Perlmutter, Joanne R. Chapman, Mason C. Wilkinson, Isaac Nevarez-Saenz, Robert L. Unckless |
| سنة النشر: |
2024 |
| المجموعة: |
Smithsonian Institution: Figshare |
| مصطلحات موضوعية: |
Medicine, Genetics, Evolutionary Biology, Ecology, Immunology, Infectious Diseases, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, two main questions, coevolutionary arms race, host fitness cost, four different species, fitness cost ), distinct functional importance, previous work demonstrated, cas9 genome editing, certain pathogens depending, natural metchnikowin alleles, div >< p, based functional differences, systemic immune responses, specificity hypothesis )?, selection may act, results provide strong, life history tradeoffs, insect amps tend, different specific pathogens, autoimmune hypothesis )?, p allele outperforming, r allele performs |
| الوصف: |
(a) Graph of Mtk expression levels (TPM, transcripts per million reads) in male and female Canton S flies either unchallenged with infection (UC) or challenged with Providencia rettgeri , 8 hours post-infection. Data from FlySexsick-seq database 71 . (b) qPCR data of Mtk gene expression with or without infection across CRISPR lines used in this study. Each data point represents a pool of 3 flies (whole bodies) either infected with Beauveria bassiana or not infected (control). qPCR based on levels of Mtk gene expression vs host rp49 housekeeping gene expression. Values denote 2 -(Δct) . Statistics are based on logistic regression and Tukey post-hoc test ( S2 Table ). (TIF) |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/_i_Mtk_i_is_expressed_at_low_baseline_levels_without_infection_and_is_highly_induced_with_infection_/25385781 |
| DOI: |
10.1371/journal.pgen.1011155.s011 |
| الاتاحة: |
https://doi.org/10.1371/journal.pgen.1011155.s011 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.61E6DB39 |
| قاعدة البيانات: |
BASE |