Academic Journal

Effects of neonicotinoid exposure on molecular and physiological indicators of honey bee immunocompetence

التفاصيل البيبلوغرافية
العنوان: Effects of neonicotinoid exposure on molecular and physiological indicators of honey bee immunocompetence
المؤلفون: Collison, Elizabeth J., Hird, Heather, Tyler, Charles R., Cresswell, James E.
المصدر: ISSN: 0044-8435.
بيانات النشر: HAL CCSD
سنة النشر: 2018
المجموعة: Archive ouverte HAL (Hyper Article en Ligne, CCSD - Centre pour la Communication Scientifique Directe)
مصطلحات موضوعية: imidacloprid, thiamethoxam, immunocompetence, antimicrobial peptide, gene expression, [SDV]Life Sciences [q-bio]
الوصف: International audience ; AbstractBee declines have been associated with various stressors including pesticides and pathogens. We separately exposed immune-challenged adult worker honey bees (Apis mellifera L.) to two neonicotinoid pesticides, thiamethoxam (10 ppb) and imidacloprid (102 ppb), by dietary delivery. We found that whereas neonicotinoid exposure weakly affected transcriptional responses of antimicrobial genes, it did not detectably affect the physiological antimicrobial response as measured by a lytic clearance assay of haemolymph. Our findings add to the evidence that transcriptional responses in immune-related genes are not yet reliable indicators of pesticide impacts on bee health, which suggests caution in their future use as biomarkers in pesticide risk assessment.
نوع الوثيقة: article in journal/newspaper
اللغة: English
Relation: hal-02973396; https://hal.archives-ouvertes.fr/hal-02973396; https://hal.archives-ouvertes.fr/hal-02973396/document; https://hal.archives-ouvertes.fr/hal-02973396/file/springer.pdf
DOI: 10.1007/s13592-017-0541-3
الاتاحة: https://hal.archives-ouvertes.fr/hal-02973396
https://hal.archives-ouvertes.fr/hal-02973396/document
https://hal.archives-ouvertes.fr/hal-02973396/file/springer.pdf
https://doi.org/10.1007/s13592-017-0541-3
Rights: info:eu-repo/semantics/OpenAccess
رقم الانضمام: edsbas.618335B4
قاعدة البيانات: BASE
الوصف
DOI:10.1007/s13592-017-0541-3