Academic Journal
Exposure to Antineoplastic Drugs Outside the Hospital Environment
العنوان: | Exposure to Antineoplastic Drugs Outside the Hospital Environment |
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المؤلفون: | Meijster, T., Fransman, W., Veldhof, R., Kromhout, H. |
بيانات النشر: | Oxford University Press |
سنة النشر: | 2006 |
المجموعة: | HighWire Press (Stanford University) |
مصطلحات موضوعية: | Article |
الوصف: | Objectives: The objectives were (i) to identify occupational populations outside hospitals working with antineoplastic drugs, (ii) to determine the size of the populations ‘at risk’, (iii) to identify major determinants and routes of exposure outside hospitals and (iv) to estimate exposure levels and frequencies relative to levels found in hospitals. Methods: The survey consisted of two phases; (i) identification of activities with potential exposure to antineoplastic drugs by literature review, interviews, questionnaires and workplace visits, (ii) exploratory measurements of exposure and surface contamination in selected sectors. Results: Eight sectors were identified with potential exposure to antineoplastic drugs: pharmaceutical industry, pharmacies, universities, veterinary medicine, nursing homes, home care, laundry facilities, and waste treatment. Four sectors were of primary concern: veterinary medicine, home care, nursing homes and industrial laundries. The populations potentially exposed in these sectors vary considerably (from several tens to thousands of workers), as do their levels of exposure. Exposure measurements collected in the veterinary medicine sector showed that workers are indeed exposed to antineoplastic drugs and, in some cases (on gloves after administration), levels were 15 times higher than levels measured during administration in hospitals. Workers sorting contaminated hospital laundry in industrial laundry facilities were exposed to antineoplastic drugs through inhalation. For the home care and nursing homes sectors the highest exposure levels were found when cleaning toilets and washing treated patients. These two sectors are expected to have the largest exposed population (5000-10 000 individuals). Conclusions: This study has resulted in a comprehensive overview of populations with potential exposure to antineoplastic drugs. Exposure levels can potentially be high compared with the hospital environment, because exposure routes are complex and awareness of the hazard (and therefore ... |
نوع الوثيقة: | text |
وصف الملف: | text/html |
اللغة: | English |
Relation: | http://annhyg.oxfordjournals.org/cgi/content/short/mel023v1; http://dx.doi.org/10.1093/annhyg/mel023 |
DOI: | 10.1093/annhyg/mel023 |
الاتاحة: | http://annhyg.oxfordjournals.org/cgi/content/short/mel023v1 https://doi.org/10.1093/annhyg/mel023 |
Rights: | Copyright (C) 2006, British Occupational Hygiene Society |
رقم الانضمام: | edsbas.60E90395 |
قاعدة البيانات: | BASE |
DOI: | 10.1093/annhyg/mel023 |
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