التفاصيل البيبلوغرافية
| العنوان: |
(A) systematic approach for estimating chemical properties ; 화학 물질의 특성 예측을 위한 시스템적 접근법 |
| المؤلفون: |
Lee, Kyoung-Ho(이경호) |
| المساهمون: |
Park, Sun-Won(박선원) |
| بيانات النشر: |
한국과학기술원 |
| سنة النشر: |
2009 |
| المجموعة: |
Korea Advanced Institute of Science and Technology: KOASAS - KAIST Open Access Self-Archiving System |
| مصطلحات موضوعية: |
systems biology, bioinformatics, group contribution method, gibbs free energy, flux balance analysis, 시스템 생물학, 생물정보학, 그룹기여법, 깁스에너지, 흐름분석법 |
| الوصف: |
학위논문(석사) - 한국과학기술원 : 생명화학공학과, 2009.2, [ v, 53 p. ] ; Thermodynamic data plays a crucial role in analyzing the biological system. Especially $\Delta G^o_r$ (standard Gibbs free energy change of a biochemical reaction) enables the forecasting of thermodynamic favorability of biochemical pathways. However, experimental data related to this theme is very limited. Therefore this research focuses on consolidating the already existing but dispersed databases. Due to the lack of such database derived from experiment, the accuracy of Group contribution method has been heightened which can predict the value of $\Delta G^o_r$ through calculation to replace the currently developed method of experimenting. Furthermore, the group contribution method has developed an automation system which has been applied to the E.coli iJR904 model for the thermodynamic analysis. ; 한국과학기술원 : 생명화학공학과 |
| نوع الوثيقة: |
other/unknown material |
| اللغة: |
English |
| الاتاحة: |
http://hdl.handle.net/10203/29465
http://library.kaist.ac.kr/index.php?TargetPageName=wSrchAllDetailView.php&bibctrlno=308723 |
| رقم الانضمام: |
edsbas.60A70668 |
| قاعدة البيانات: |
BASE |