Academic Journal
Emerging evidence and treatment paradigm of non-small cell lung cancer
| العنوان: | Emerging evidence and treatment paradigm of non-small cell lung cancer |
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| المؤلفون: | Liu, Si-Yang Maggie, Zheng, Mei-Mei, Pan, Yi, Liu, Si-Yang, Li, Yangqiu, Wu, Yi-Long |
| المساهمون: | National Natural Science Foundation of China, China Postdoctoral Science Foundation, Key Lab System Project of Guangdong Science and Technology Department, Guangdong Provincial Key Lab of Translational Medicine in Lung Cancer, Guangdong Provincial People's Hospital Scientific Research Funds for Leading Medical Talents in Guangdong Province |
| المصدر: | Journal of Hematology & Oncology ; volume 16, issue 1 ; ISSN 1756-8722 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2023 |
| الوصف: | Research on biomarker-driven therapy and immune check-point blockade in non-small cell lung cancer (NSCLC) is rapidly evolving. The width and depth of clinical trials have also dramatically improved in an unprecedented speed. The personalized treatment paradigm evolved every year. In this review, we summarize the promising agents that have shifted the treatment paradigm for NSCLC patients across all stages, including targeted therapy and immunotherapy using checkpoint inhibitors. Based on recent evidence, we propose treatment algorithms for NSCLC and propose several unsolved clinical issues, which are being explored in ongoing clinical trials. The results of these trials are likely to impact future clinical practice. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1186/s13045-023-01436-2 |
| DOI: | 10.1186/s13045-023-01436-2.pdf |
| DOI: | 10.1186/s13045-023-01436-2/fulltext.html |
| الاتاحة: | http://dx.doi.org/10.1186/s13045-023-01436-2 https://link.springer.com/content/pdf/10.1186/s13045-023-01436-2.pdf https://link.springer.com/article/10.1186/s13045-023-01436-2/fulltext.html |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.601ADC9C |
| قاعدة البيانات: | BASE |
| DOI: | 10.1186/s13045-023-01436-2 |
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