Academic Journal

Tracking regional brain growth up to age 13 in children born term and very preterm

التفاصيل البيبلوغرافية
العنوان: Tracking regional brain growth up to age 13 in children born term and very preterm
المؤلفون: Thompson, DK, Matthews, LG, Alexander, B, Lee, KJ, Kelly, CE, Adamson, CL, Hunt, RW, Cheong, JLY, Spencer-Smith, M, Neil, JJ, Seal, ML, Inder, TE, Doyle, LW, Anderson, PJ
بيانات النشر: NATURE PUBLISHING GROUP
سنة النشر: 2020
المجموعة: The University of Melbourne: Digital Repository
الوصف: Serial regional brain growth from the newborn period to adolescence has not been described. Here, we measured regional brain growth in 216 very preterm (VP) and 45 full-term (FT) children. Brain MRI was performed at term-equivalent age, 7 and 13 years in 82 regions. Brain volumes increased between term-equivalent and 7 years, with faster growth in the FT than VP group. Perinatal brain abnormality was associated with less increase in brain volume between term-equivalent and 7 years in the VP group. Between 7 and 13 years, volumes were relatively stable, with some subcortical and cortical regions increasing while others reduced. Notably, VP infants continued to lag, with overall brain size generally less than that of FT peers at 13 years. Parieto-frontal growth, mainly between 7 and 13 years in FT children, was associated with higher intelligence at 13 years. This study improves understanding of typical and atypical regional brain growth.
نوع الوثيقة: article in journal/newspaper
اللغة: English
تدمد: 2041-1723
Relation: NHMRC/628371; pii: 10.1038/s41467-020-14334-9; Thompson, D. K., Matthews, L. G., Alexander, B., Lee, K. J., Kelly, C. E., Adamson, C. L., Hunt, R. W., Cheong, J. L. Y., Spencer-Smith, M., Neil, J. J., Seal, M. L., Inder, T. E., Doyle, L. W. & Anderson, P. J. (2020). Tracking regional brain growth up to age 13 in children born term and very preterm. NATURE COMMUNICATIONS, 11 (1), https://doi.org/10.1038/s41467-020-14334-9.; http://hdl.handle.net/11343/245612
الاتاحة: http://hdl.handle.net/11343/245612
Rights: CC BY ; https://creativecommons.org/licenses/by/4.0
رقم الانضمام: edsbas.5FA67D64
قاعدة البيانات: BASE