التفاصيل البيبلوغرافية
| العنوان: |
Avaliação da atividade moduladora e citotóxica do óleo essencial das folhas de Hyptis martiusii Benth |
| المؤلفون: |
Sobreira Dantas Nóbrega de Figueirêdo, Francisco Rodolpho, Bitu Primo, Ana Jaqueline, Brito Monteiro, Álefe, Relison Tintino, Saulo, de Araújo Delmondes, Gyllyandeson, Dos Santos Sales, Valterlúcio, De Souza Rodrigues, Cristina Kelly, Bezerra Felipe, Cicero Francisco, Melo Coutinho, Henrique Douglas, Kerntopf, Marta Regina |
| المصدر: |
Ciencias de la salud, ISSN 1692-7273, Vol. 16, Nº. 1, 2018, pags. 49-58 |
| سنة النشر: |
2018 |
| المجموعة: |
Dialnet - Portada de revistas (Universidad de La Rioja) |
| مصطلحات موضوعية: |
actividad antibacteriana, actividad citotóxica, cidreira do campo, Hyptis martiusii, aceites esenciales, Antibacterial activity, cytotoxic activity, essential oil, atividade antibacteriana, atividade citotóxica, óleo essencial |
| الوصف: |
The species Hyptis martiusii Benth. is popularly known as “cidreira do campo”. It has multiple biological properties, including antifungal, anti-inflammatory, and insecticide. The aim of this study was to investigate the modulating activity of the essential oil of fresh leaves of Hyptis martiusii in association with different antibiotics against the bacteria Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa, as also the cytotoxic activity of this species. The study used the MIC (minimum inhibitory concentration) as a way of assessing the modulation using an inoculation of 100 microliters of each bacterial strain. Cytotoxicity tests were conducted using in vitro culture of mouse connective tissue cells (fibroblasts of mammals). The research demonstrated that the essential oil from leaves of Hyptis martiusii Benth —oehm— presented synergism only in association with the antibiotics gentamicin and imipenem against the bacteria Pseudomonas aeruginosa and Escherichia coli. However, it presented antagonism in association with amikacin, gentamicin and imipenem against the three studied bacteria. In addition to the cipro oxacin showed no relevant results. In relation to the cytotoxic activity, the lethal concentration (LC50) exhibited a value of 263.12 μg/ml. Finally, we can say that H. Martiusii presents a synergistic cytotoxic activity against the evaluated bacteria. ; A espécie Hyptis martiusii Benth é popularmente conhecida como “cidreira do campo”. Possui várias atividades biológicas, dentre elas atividades antifúngica, antiin amatória e inseticida. O objetivo deste trabalho foi investigar a atividade moduladora do óleo essencial das folhas frescas de Hyptis martiusii em associação com diferentes antibióticos frente às bactérias Staphylococcus aureus, Escherichia coli e Pseudomonas aeruginosa, como também a atividade citotóxica da espécie. O estudo utilizou a cim (con- centração inibitória mínima) como forma de avaliação da modulação usando uma inoculação de 100 microlitros de cada estirpe ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
Portuguese |
| Relation: |
https://dialnet.unirioja.es/servlet/oaiart?codigo=6324071; (Revista) ISSN 1692-7273 |
| الاتاحة: |
https://dialnet.unirioja.es/servlet/oaiart?codigo=6324071 |
| Rights: |
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| رقم الانضمام: |
edsbas.5F2E1F5A |
| قاعدة البيانات: |
BASE |