Academic Journal
A Prospective Observational Investigation of the Etiological Profile and Prognosis of Children with Status Epilepticus Involved in a Tertiary Care Hospital
| العنوان: | A Prospective Observational Investigation of the Etiological Profile and Prognosis of Children with Status Epilepticus Involved in a Tertiary Care Hospital |
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| المؤلفون: | Pawan Kumar, Anil Kumar Tiwari, K. M. Manisha, Kaushalendra Kumar Singh |
| المصدر: | International Journal of Pharmaceutical and Clinical Research, 15(11), 1426-1431, (2023-11-30) |
| بيانات النشر: | International Journal of Pharmaceutical and Clinical Research |
| سنة النشر: | 2023 |
| المجموعة: | Zenodo |
| مصطلحات موضوعية: | mortality, meningitis, febrile state, anemia, and antiepileptic drugs |
| الوصف: | Objective: The purpose of this research was to describe the clinical-etiological profile of Status Epilepticus (SE) in children under the age of 11 and to investigate the risk factors, etiologies, outcomes at the end of hospitalization, and predictors of favorable/unfavourable outcomes in SE. Method: This was a hospital base prospective study of 100 children under the age of 11 who were admitted consecutively with SE to a pediatric intensive care unit of a tertiary care referral hospital in Patna Medical College & Hospital, Patna for a year, from April 2021 to April 2022, were enrolled in the study. The principal investigator gathered and entered the data regarding the parameters in a standardized proforma after a thorough review and necessary inquiries. The final result was documented after the patient’s hospital stay. The acquired data were evaluated to find important variables that might predict the result and the risk factors for RSE. Results: After infancy, the age range of 2 to 5 years was reported to have the highest prevalence of SE. 48.7% of cases involved girls, while 51.3% involved boys. Meningoencephalitis and febrile status were the two most frequent causes of status. Anemia was found to be a risk factor (odds ratio=8.67) and to be substantially linked with RSE (p value=0.002). 8 (8%) of the kids died. Moreover, a worse result was seen more frequently in children who remained pain sensitive or unresponsive 5 hours following seizure control (p-value <0.02). The advancement of RSE and worse results were substantially linked to delaying the administration of the first anti-epileptic drug (AED). Conclusion: Anemia and a delay in starting the first AED were discovered to be strongly linked with RSE. Also, there was a strong correlation between poor outcomes and kids who were still in pain or unresponsive 6 hours following seizure control. ; Objective: The purpose of this research was to describe the clinical-etiological profile of Status Epilepticus (SE) in children under the age of 11 and to ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | https://doi.org/10.5281/zenodo.11238118; https://doi.org/10.5281/zenodo.11238119; oai:zenodo.org:11238119; https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue11,Article239.pdf |
| DOI: | 10.5281/zenodo.11238119 |
| الاتاحة: | https://doi.org/10.5281/zenodo.11238119 https://impactfactor.org/PDF/IJPCR/15/IJPCR,Vol15,Issue11,Article239.pdf |
| Rights: | info:eu-repo/semantics/openAccess ; Creative Commons Attribution 4.0 International ; https://creativecommons.org/licenses/by/4.0/legalcode |
| رقم الانضمام: | edsbas.5D729406 |
| قاعدة البيانات: | BASE |
| DOI: | 10.5281/zenodo.11238119 |
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