Academic Journal
Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae)
العنوان: | Metabolites from Microbes Isolated from the Skin of the Panamanian Rocket Frog Colostethus panamansis (Anura: Dendrobatidae) |
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المؤلفون: | Christian Martin H., Roberto Ibáñez, Louis-Félix Nothias, Andrés Mauricio Caraballo-Rodríguez, Pieter C. Dorrestein, Marcelino Gutiérrez |
المصدر: | Metabolites, Vol 10, Iss 406, p 406 (2020) |
بيانات النشر: | MDPI AG |
سنة النشر: | 2020 |
المجموعة: | Directory of Open Access Journals: DOAJ Articles |
مصطلحات موضوعية: | 3D molecular cartography, Colostethus panamansis, Dendrobatidae, skin-associated bacteria, 16S rRNA sequencing, feature-based molecular networking, Microbiology, QR1-502 |
الوصف: | The Panamanian rocket frog Colostethus panamansis (family Dendrobatidae) has been affected by chytridiomycosis, a deadly disease caused by the fungus Batrachochytrium dendrobatidis ( Bd ). While there are still uninfected frogs, we set out to isolate microbes from anatomically distinct regions in an effort to create a cultivable resource within Panama for potential drug/agricultural/ecological applications that perhaps could also be used as part of a strategy to protect frogs from infections. To understand if there are specific anatomies that should be explored in future applications of this resource, we mapped skin-associated bacteria of C. panamansis and their metabolite production potential by mass spectrometry on a 3D model. Our results indicate that five bacterial families (Enterobacteriaceae, Comamonadaceae, Aeromonadaceae, Staphylococcaceae and Pseudomonadaceae) dominate the cultivable microbes from the skin of C. panamansis . The combination of microbial classification and molecular analysis in relation to the anti- Bd inhibitory databases reveals the resource has future potential for amphibian conservation. |
نوع الوثيقة: | article in journal/newspaper |
اللغة: | English |
تدمد: | 2218-1989 |
Relation: | https://www.mdpi.com/2218-1989/10/10/406; https://doaj.org/toc/2218-1989; https://doaj.org/article/ef544b53515c43029e17e3ad0e19cacf |
DOI: | 10.3390/metabo10100406 |
الاتاحة: | https://doi.org/10.3390/metabo10100406 https://doaj.org/article/ef544b53515c43029e17e3ad0e19cacf |
رقم الانضمام: | edsbas.5D6D5C76 |
قاعدة البيانات: | BASE |
تدمد: | 22181989 |
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DOI: | 10.3390/metabo10100406 |