Academic Journal
Early Detection of Emergent Extensively Drug-Resistant Tuberculosis by Flow Cytometry-Based Phenotyping and Whole-Genome Sequencing
| العنوان: | Early Detection of Emergent Extensively Drug-Resistant Tuberculosis by Flow Cytometry-Based Phenotyping and Whole-Genome Sequencing |
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| المؤلفون: | O’Donnell, Max R., Larsen, Michelle H., Brown, Tyler S., Jain, Paras, Munsamy, Vanisha, Wolf, Allison, Uccellini, Lorenzo, Karim, Farina, de Oliveira, Tulio, Mathema, Barun, Jacobs, William R., Pym, Alexander |
| المساهمون: | Doris Duke Charitable Foundation, HHS | NIH | NIH Clinical Center, HHS | NIH | National Institute of Allergy and Infectious Diseases |
| المصدر: | Antimicrobial Agents and Chemotherapy ; volume 63, issue 4 ; ISSN 0066-4804 1098-6596 |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 2019 |
| الوصف: | A critical gap in tuberculosis (TB) treatment is detection of emergent drug resistance. We hypothesized that advanced phenotyping with whole-genome sequencing (WGS) will detect low-frequency Mycobacterium tuberculosis drug resistance. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1128/aac.01834-18 |
| DOI: | 10.1128/AAC.01834-18 |
| الاتاحة: | http://dx.doi.org/10.1128/aac.01834-18 https://journals.asm.org/doi/pdf/10.1128/AAC.01834-18 |
| Rights: | https://journals.asm.org/non-commercial-tdm-license |
| رقم الانضمام: | edsbas.5C9FFA4D |
| قاعدة البيانات: | BASE |
| DOI: | 10.1128/aac.01834-18 |
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