Academic Journal
Age-Specific Seroprevalences of Merkel Cell Polyomavirus, Human Polyomaviruses 6, 7, and 9, and Trichodysplasia Spinulosa-Associated Polyomavirus
| العنوان: | Age-Specific Seroprevalences of Merkel Cell Polyomavirus, Human Polyomaviruses 6, 7, and 9, and Trichodysplasia Spinulosa-Associated Polyomavirus |
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| المؤلفون: | Nicol, Jérôme T. J., Robinot, Rémy, Carpentier, Audrey, Carandina, Giovanni, Mazzoni, Elisa, Tognon, Mauro, Touzé, Antoine, Coursaget, Pierre |
| المصدر: | Clinical and Vaccine Immunology ; volume 20, issue 3, page 363-368 ; ISSN 1556-6811 1556-679X |
| بيانات النشر: | American Society for Microbiology |
| سنة النشر: | 2013 |
| الوصف: | Six new human polyomaviruses have been identified since 2008 (Merkel cell polyomavirus [MCPyV], human polyomavirus 6 [HPyV6], HPyV7, HPyV9, trichodysplasia spinulosa polyomavirus [TSPyV], and Malawi polyomavirus [MWPyV]). The presence of specific antibodies against MCPyV, HPyV6, HPyV7, HPyV9, and TSPyV in 828 Italian subjects aged 1 to 100 years was investigated by virus-like particle-based enzyme-linked immunosorbent assays (ELISAs). The findings indicate that all of these new polyomaviruses circulate widely in humans, with seroprevalences in adulthood ranging from 39.4% for HPyV9 to 87.1% for MCPyV, and that primary exposure is most intense in childhood, with the exception of HPyV7 and HPyV9, for which the seroprevalence increased throughout life. The proportion of subjects with high antibody titers was found to increase with age for MCPyV and to decrease with age for TSPyV. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1128/cvi.00438-12 |
| DOI: | 10.1128/CVI.00438-12 |
| الاتاحة: | http://dx.doi.org/10.1128/cvi.00438-12 https://syndication.highwire.org/content/doi/10.1128/CVI.00438-12 |
| رقم الانضمام: | edsbas.5BFDB83A |
| قاعدة البيانات: | BASE |
| DOI: | 10.1128/cvi.00438-12 |
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