Academic Journal
Towards annotating the plant epigenome: the Arabidopsis thaliana small RNA locus map
| العنوان: | Towards annotating the plant epigenome: the Arabidopsis thaliana small RNA locus map |
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| المؤلفون: | Hardcastle, Thomas J., Müller, Sebastian Y., Baulcombe, David C. |
| المصدر: | Scientific Reports ; volume 8, issue 1 ; ISSN 2045-2322 |
| بيانات النشر: | Springer Science and Business Media LLC |
| سنة النشر: | 2018 |
| الوصف: | Based on 98 public and internal small RNA high throughput sequencing libraries, we mapped small RNAs to the genome of the model organism Arabidopsis thaliana and defined loci based on their expression using an empirical Bayesian approach. The resulting loci were subsequently classified based on their genetic and epigenetic context as well as their expression properties. We present the results of this classification, which broadly conforms to previously reported divisions between transcriptional and post-transcriptional gene silencing small RNAs, and to PolIV and PolV dependencies. However, we are able to demonstrate the existence of further subdivisions in the small RNA population of functional significance. Moreover, we present a framework for similar analyses of small RNA populations in all species. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1038/s41598-018-24515-8 |
| الاتاحة: | http://dx.doi.org/10.1038/s41598-018-24515-8 https://www.nature.com/articles/s41598-018-24515-8.pdf https://www.nature.com/articles/s41598-018-24515-8 |
| Rights: | https://creativecommons.org/licenses/by/4.0 ; https://creativecommons.org/licenses/by/4.0 |
| رقم الانضمام: | edsbas.5BB30CD7 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1038/s41598-018-24515-8 |
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