Academic Journal
Detection and localization of gold nanoshells inside cells: near-field approximation
| العنوان: | Detection and localization of gold nanoshells inside cells: near-field approximation |
|---|---|
| المؤلفون: | D'Acunto, Mario, Cricenti, Antonio, Danti, Serena, Dinarelli, Simone, Luce, Marco, Moroni, Davide, Salvetti, Ovidio |
| المساهمون: | Marija Strojnik, Antoni Rogalski, Mario D'Acunto |
| المصدر: | In: Applied Optics, vol. 55 (34) pp. D11 - D16. Special issue: Advances in Infrared Technology and Applications. Marija Strojnik, Antoni Rogalski, Mario D'Acunto (eds.). Optical Society of America, 2016. |
| بيانات النشر: | Optical Society of America |
| سنة النشر: | 2016 |
| المجموعة: | PUMAlab (ISTI CNR - Consiglio Nazionale delle Ricerche / National Research Council) |
| مصطلحات موضوعية: | Near-Field SNOM, Core-gold nanoshells, Near-infrared, Tissue transparency window, H9c2 mouse cell, info:eu-repo/classification/acm/G.1.8 Partial Differential Equations, info:eu-repo/classification/msc/35Q60 PDEs in connection with optics and electromagnetic theory |
| الوصف: | The optical properties of metal nanoparticles play a fundamental role for their use in a wide range of applications. In hyperthermia treatment, for example, gold nanoshells (NSs, dielectric core+gold shell) pre-embedded in a cancer cell absorb energy when exposed to appropriate wavelengths of a laser beam and heat up, thereby destroying the cancer cell. In this process, nevertheless, healthy tissues (not targeted by the NSs) along the laser path are not affected; this is because most biological soft tissues have a relatively low light absorption coefficient in the near-infrared (NIR) regions-a characteristic known as the tissue optical window. Over such a window, NIR light transmits through the tissues with scattering-limited attenuation and minimal heating, thereby avoiding damage to healthy tissues. As a consequence, the identification of NSs assumed a fundamental role for the further development of such cancer treatment. Recently, we have demonstrated the possibility to identify 100-150 nm diameter gold NSs inside mouse cells using a scanning near-optical microscope (SNOM). In this paper, we provide a numerical demonstration that the SNOM is able to locate NSs inside the cell with a particle-aperture distance of about 100 nm. This result was obtained by developing an analytical approach based on the calculation of the dyadic Green function in the near-field approximation. The implications of our findings will remarkably affect further investigations on the interaction between NSs and biological systems. ; In questo lavoro, ? stata calcolata la possibile localizzazione di una nanoparticella di oro internalizzata in una cellula di topo e precedentemente identificata con uno Microscopio di sonda a campo prossimo, SNOM. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/url/https://www.osapublishing.org/ao/abstract.cfm?uri=ao-55-34-D11; info:eu-repo/semantics/altIdentifier/issn/1559-128X; http://puma.isti.cnr.it/dfdownloadnew.php?ident=cnr.isti/cnr.isti/2016-A0-045; http://puma.isti.cnr.it/rmydownload.php?filename=cnr.isti/cnr.isti/2016-A0-045/2016-A0-045.pdf |
| الاتاحة: | http://puma.isti.cnr.it/dfdownloadnew.php?ident=cnr.isti/cnr.isti/2016-A0-045 http://puma.isti.cnr.it/rmydownload.php?filename=cnr.isti/cnr.isti/2016-A0-045/2016-A0-045.pdf |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5B8061B6 |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |