Academic Journal
Capillary isotachophoresis with ESI-MS detection: Methodology for highly sensitive analysis of ibuprofen and diclofenac in waters
| العنوان: | Capillary isotachophoresis with ESI-MS detection: Methodology for highly sensitive analysis of ibuprofen and diclofenac in waters |
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| المؤلفون: | Malá, Z. (Zdeňka), Gebauer, P. (Petr), Boček, P. (Petr) |
| سنة النشر: | 2016 |
| المجموعة: | The Czech Academy of Sciences: Publication Activity (ASEP) / Akademie věd ČR - Publikační činnost |
| مصطلحات موضوعية: | isotachophoresis, mass spectrometric detection, Diclofenac, Ibuprofen |
| الوصف: | The possibilities of reaching higher sensitivity in capillary electrophoretic analyses of complex samples with ESI-MS detection were investigated on the example of analysis of diclofenac and ibuprofen in waters. The applied separation approach is based on application of isotachophoresis that ensures permanent stacking of analytes until they reach the detector. Investigation of the possibilities of MS detector optimization have shown that optimization of fragmentor voltage and working in the SIM mode with collection of data for multiple fragments both increases the method specificity and approx. doubles its sensitivity. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 0003-2670 1873-4324 |
| Relation: | urn:pissn: 0003-2670; urn:eissn: 1873-4324; http://hdl.handle.net/11104/0256621 |
| DOI: | 10.1016/j.aca.2015.11.040 |
| الاتاحة: | https://doi.org/10.1016/j.aca.2015.11.040 http://hdl.handle.net/11104/0256621 |
| Rights: | info:eu-repo/semantics/restrictedAccess |
| رقم الانضمام: | edsbas.5AFDA008 |
| قاعدة البيانات: | BASE |
| تدمد: | 00032670 18734324 |
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| DOI: | 10.1016/j.aca.2015.11.040 |