Effects of bacterial genotoxins on P62/SQSTM1 bodies localization and LC3 in hepatic cell lines.

التفاصيل البيبلوغرافية
العنوان: Effects of bacterial genotoxins on P62/SQSTM1 bodies localization and LC3 in hepatic cell lines.
المؤلفون: Wencan He (3845095), Lamia Azzi-Martin (7444901), Valérie Velasco (154339), Philippe Lehours (190147), Pierre Dubus (225300), Mojgan Djavaheri-Mergny (7444916), Armelle Ménard (222043)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Biochemistry, Microbiology, Cell Biology, Genetics, Molecular Biology, Immunology, Developmental Biology, Cancer, Science Policy, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, autophagosome marker LC 3, γ H 2AX foci, cytolethal distending toxin, nucleoplasmic reticulum formation, HT, autophagy, hepatic cell lines, RNA, ATG, Helicobacter hepaticus CDT, NR, UNR, DNA damage, genome microarray-based identification, micronuclei-like structures, genotoxin-induced apoptotic cell death
الوصف: Hep3B cells were processed as in Fig 7 . Fluorescent staining was observed using wide field fluorescence imaging. (A) Images of Hep3B cells: γH2AX (red), LC3 (green), DAPI (blue). (B) Images of Hep3B cells: nuclear lamina (red), P62/SQSTM1 (green), DAPI (blue). Scale bars, 20 μm. Yellow arrowheads indicate extra-nuclear structures containing chromatin. Blue arrowheads indicate P62/SQSTM1 aggregates tightly connected all along the nuclear membrane. Yellow boxes correspond to enlargement of micronucleus-like structures with DAPI. White boxes on the right correspond to enlargement of the merge. Abbreviations: DAPI, 4′, 6′-diamidino-2-phenylindol; NR, nucleoplasmic reticulum.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Effects_of_bacterial_genotoxins_on_P62_SQSTM1_bodies_localization_and_LC3_in_hepatic_cell_lines_/14166219
DOI: 10.1371/journal.ppat.1009320.g008
الاتاحة: https://doi.org/10.1371/journal.ppat.1009320.g008
Rights: CC BY 4.0
رقم الانضمام: edsbas.5A6B8207
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.ppat.1009320.g008