Academic Journal
Prevalence and Risk Factors of Deep Venous Thrombosis in Intensive Inpatient Neurorehabilitation Unit
| العنوان: | Prevalence and Risk Factors of Deep Venous Thrombosis in Intensive Inpatient Neurorehabilitation Unit |
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| المؤلفون: | Maria Elena Pugliese, Riccardo Battaglia, Maria Ursino, Lucia Francesca Lucca, Maria Quintieri, Martina Vatrano, Paolo Tonin, Antonio Cerasa |
| المصدر: | Healthcare, Vol 12, Iss 9, p 936 (2024) |
| بيانات النشر: | MDPI AG |
| سنة النشر: | 2024 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | deep venous thrombosis, rehabilitation, D-dimer, compressive ultrasonography, severe brain injury, stroke, Medicine |
| الوصف: | Venous thromboembolism (VTE) (deep vein thrombosis and its complication, pulmonary embolism) is a major cause of morbidity and mortality in hospitalized patients and about 7% of these cases are due to immobility secondary to a neurological impairment. Acquired brain injury (ABI) has also been recognized as one of the main risk factors for VTE. Numerous epidemiological studies have been conducted to assess the risk factors for VTE in institutionalized polytrauma patients, although there is a lack of information about neurorehabilitation wards. Since VTE is often undiagnosed, this prospective study aimed to determine the prevalence and clinical characteristics of lower-limb deep venous thrombosis (DVT) in ABI patients at neurorehabilitation admission. Methods: ABI patients were screened for DVT on admission to the intensive rehabilitation unit (IRU) with compression ultrasonography and basal D-dimer assay and were daily clinically monitored until discharge. A total of 127 consecutive ABI patients (mean age: 60.1 ± 17.6 years; 63% male; time from event: 30.9 ± 22.1 days; rehabilitation time in IRU: 84.6 ± 58.4 days) were enrolled. Results: On admission to the IRU, the DVT prevalence was about 8.6%. The mean D-dimer level in patients with DVT was significantly higher than in patients without DVT (6 ± 0.9 vs. 1.97 ± 1.61, p -value = 0.0001). ABI patients with DVT did not show any significant clinical characteristics with respect to ABI without DVT, although a prevalence of hemorrhagic strokes and patients originating from the Intensive Care Unit and Neurosurgery ward was revealed. During the rehabilitation period, patients with DVT showed a significant difference in pharmacological DVT prophylaxis (high prevalence of nadroparin with 27.3% vs. 1.7%, p -value = 0.04) and a prevalence of transfers in critical awards (36% versus 9.5% of patients without DVT, p -value = 0.05). The mortality rate was similar in the two groups. Conclusions: Our research offers a more comprehensive view of the clinical development of DVT ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2227-9032 |
| Relation: | https://www.mdpi.com/2227-9032/12/9/936; https://doaj.org/toc/2227-9032; https://doaj.org/article/7a5ad98305f643658bb8726c41aeced9 |
| DOI: | 10.3390/healthcare12090936 |
| الاتاحة: | https://doi.org/10.3390/healthcare12090936 https://doaj.org/article/7a5ad98305f643658bb8726c41aeced9 |
| رقم الانضمام: | edsbas.5A3135C7 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 22279032 |
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| DOI: | 10.3390/healthcare12090936 |