Academic Journal

‘I am afraid you will see the stain on my soul’: Direct gaze neural processing in individuals with PTSD after moral injury recall

التفاصيل البيبلوغرافية
العنوان: ‘I am afraid you will see the stain on my soul’: Direct gaze neural processing in individuals with PTSD after moral injury recall
المؤلفون: Andrews, Krysta, Lloyd, Chantelle S, Densmore, Maria, Kearney, Breanne E, Harricharan, Sherain, McKinnon, Margaret C, Théberge, Jean, Jetly, Rakesh, Lanius, Ruth A
المساهمون: Canada Foundation for Innovation, Canadian Institute for Military and Veteran Health Research, The Centre of Excellence on PTSD, Green Shield Canada, Institute of Neurosciences, Mental Health and Addiction
المصدر: Social Cognitive and Affective Neuroscience ; volume 18, issue 1 ; ISSN 1749-5016 1749-5024
بيانات النشر: Oxford University Press (OUP)
سنة النشر: 2023
الوصف: Direct eye contact is essential to understanding others’ thoughts and feelings in social interactions. However, those with post-traumatic stress disorder (PTSD) and exposure to moral injury (MI) may exhibit altered theory-of-mind (ToM)/mentalizing processes and experience shame which precludes one’s capacity for direct eye contact. We investigated blood oxygenation level-dependent (BOLD) responses associated with direct vs averted gaze using a virtual reality paradigm in individuals with PTSD (n = 28) relative to healthy controls (n = 18) following recall of a MI vs a neutral memory. Associations between BOLD responses and clinical symptomatology were also assessed. After MI recall, individuals with PTSD showed greater activation in the right temporoparietal junction as compared to controls (T = 4.83; pFDR < 0.001; k = 237) during direct gaze. No significant activation occurred during direct gaze after neutral memory recall. Further, a significant positive correlation was found between feelings of distress and right medial superior frontal gyrus activation in individuals with PTSD (T = 5.03; pFDR = 0.049; k = 123). These findings suggest that direct gaze after MI recall prompts compensatory ToM/mentalizing processing. Implications for future interventions aimed at mitigating the effects of PTSD on social functioning are discussed.
نوع الوثيقة: article in journal/newspaper
اللغة: English
DOI: 10.1093/scan/nsad053
الاتاحة: http://dx.doi.org/10.1093/scan/nsad053
https://academic.oup.com/scan/article-pdf/18/1/nsad053/53975193/nsad053.pdf
Rights: https://creativecommons.org/licenses/by/4.0/
رقم الانضمام: edsbas.5964CB59
قاعدة البيانات: BASE