Academic Journal
Quantitative Mid‐Infrared Plasmonic Biosensing on Scalable Graphene Nanostructures
| العنوان: | Quantitative Mid‐Infrared Plasmonic Biosensing on Scalable Graphene Nanostructures |
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| المؤلفون: | Nestor Jr. Bareza, Ewelina Wajs, Bruno Paulillo, Antti Tullila, Hannakaisa Jaatinen, Roberto Milani, Camilla Dore, Agustin Mihi, Tarja K. Nevanen, Valerio Pruneri |
| المصدر: | Advanced Materials Interfaces, Vol 10, Iss 2, Pp n/a-n/a (2023) |
| بيانات النشر: | Wiley-VCH |
| سنة النشر: | 2023 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | antibody, graphene plasmonics, graphene sensor, mid‐infrared biosensor, SEIRA, vitamin B 12, Physics, QC1-999, Technology |
| الوصف: | Graphene nanostructures, exhibiting tunable and nanoscale‐confined mid‐infrared (mid‐IR) plasmons, prevail as a powerful spectroscopic platform for novel surface‐enhanced molecular identification. Particularly, graphene shows exciting opportunities for biosensing applications due to its versatile functionalization methods with different biomolecular building blocks (e.g., enzymes, proteins, and DNA). Here, a quantitative bioassay based on the mid‐IR localized surface plasmon resonance (LSPR) modulation in functionalized graphene nanostructures is demonstrated. Specifically, vitamin B12 (vB12) using the specific recognition elements on modified graphene nanoribbons (i.e., pyrene linkers via π − π stacking + anti‐vB12 antibody fragments via amide bond) is detected. Different concentrations of vB12 spotted on an arrayed panel of a single chip are quantified by the graphene LSPR shifts, where a limit of detection (LOD) of 53.5 ng mL−1 is obtained. The upscaling potential of the bioassay using large area nanostructured graphene films produced by nanoimprinting 2D hole arrays is illustrated. The integration of quantitative bioassay with scalable graphene nanostructures shows promising routes of graphene‐based mid‐IR platforms toward prospective industrial applications. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2196-7350 |
| Relation: | https://doi.org/10.1002/admi.202201699; https://doaj.org/toc/2196-7350; https://doaj.org/article/0e3f6a95aa214def9cf115b427c6f4d3 |
| DOI: | 10.1002/admi.202201699 |
| الاتاحة: | https://doi.org/10.1002/admi.202201699 https://doaj.org/article/0e3f6a95aa214def9cf115b427c6f4d3 |
| رقم الانضمام: | edsbas.58CE1F48 |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 21967350 |
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| DOI: | 10.1002/admi.202201699 |