التفاصيل البيبلوغرافية
| العنوان: |
Allergenicity reduction of cow's milk proteins using latex peptidases |
| المؤلفون: |
Oliveira, João P. B., Candreva, Ángela María, Rizzo, Gaston Pascual, Ramos, Márcio V., Oliveira, Jefferson S., Oliveira, Hermógenes D., Ary, Maria B., Docena, Guillermo H., Freitas, Cleverson D. T. |
| بيانات النشر: |
Elsevier |
| المجموعة: |
CONICET Digital (Consejo Nacional de Investigaciones Científicas y Técnicas) |
| مصطلحات موضوعية: |
Milk Allergy, latex peptidases, novel hypoallergenic formulas, https://purl.org/becyt/ford/3.4, https://purl.org/becyt/ford/3 |
| الوصف: |
The present study evaluated four laticifer fluids as a novel source of peptidases capable of hydrolyzing proteins in cow´s milk. The latex peptidases from Calotropis procera (CpLP), Cryptostegia grandiflora (CgLP), and Carica papaya (CapLP) were able to perform total hydrolysis of caseins after 30 min at pH 6.5, as confirmed by a significant reduction in the residual antigenicity. Casein hydrolysis by Plumeria rubra latex peptidases (PrLP) was negligible. Moreover, whey proteins were more resistant to proteolysis by latex peptidases; however, heat pretreatment of the whey proteins enhanced the degree of hydrolysis and reduced the residual antigenicity of the hydrolysates. The in vivo assays show that the cow´s milk proteins hydrolysed by CgLP and CapLP exhibited no immune reactions in mice allergic to cow´s milk, similar to a commercial partially hydrolysed formula. Thus, these peptidases are promising enzymes for the development of novel hypoallergenic formulas for children with a milk allergy. ; Fil: Oliveira, João P. B. Universidade Estadual do Ceará; Brasil ; Fil: Candreva, Ángela María. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; Argentina ; Fil: Rizzo, Gaston Pascual. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - La Plata. Instituto de Estudios Inmunológicos y Fisiopatológicos. Universidad Nacional de La Plata. Facultad de Ciencias Exactas. Instituto de Estudios Inmunológicos y Fisiopatológicos; Argentina ; Fil: Ramos, Márcio V. Universidade Estadual do Ceará; Brasil ; Fil: Oliveira, Jefferson S. Universidade Estadual do Ceará; Brasil ; Fil: Oliveira, Hermógenes D. Universidade Federal Do Piaui.; Brasil ; Fil: Ary, Maria B. Universidade Estadual do Ceará; Brasil ; Fil: Docena, Guillermo H. Consejo Nacional de ... |
| نوع الوثيقة: |
article in journal/newspaper |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| تدمد: |
0308-8146 |
| Relation: |
info:eu-repo/semantics/altIdentifier/url/https://www.sciencedirect.com/science/article/pii/S0308814619301980; http://hdl.handle.net/11336/131672; Oliveira, João P. B.; Candreva, Ángela María; Rizzo, Gaston Pascual; Ramos, Márcio V.; Oliveira, Jefferson S.; et al.; Allergenicity reduction of cow's milk proteins using latex peptidases; Elsevier; Food Chemistry; 284; 6-2019; 245-253; CONICET Digital; CONICET |
| الاتاحة: |
http://hdl.handle.net/11336/131672 |
| Rights: |
info:eu-repo/semantics/openAccess ; https://creativecommons.org/licenses/by-nc-sa/2.5/ar/ |
| رقم الانضمام: |
edsbas.574A1A79 |
| قاعدة البيانات: |
BASE |