التفاصيل البيبلوغرافية
| العنوان: |
The Role of the VEGF Family in Atherosclerosis Development and Its Potential as Treatment Targets |
| المؤلفون: |
Siarhei A. Dabravolski, Victoria A. Khotina, Andrey V. Omelchenko, Vladislav A. Kalmykov, Alexander N. Orekhov |
| المصدر: |
International Journal of Molecular Sciences; Volume 23; Issue 2; Pages: 931 |
| بيانات النشر: |
Multidisciplinary Digital Publishing Institute |
| سنة النشر: |
2022 |
| المجموعة: |
MDPI Open Access Publishing |
| مصطلحات موضوعية: |
atherosclerosis, angiogenesis, inflammation, VEGF, cardiovascular diseases |
| جغرافية الموضوع: |
agris |
| الوصف: |
The vascular endothelial growth factor (VEGF) family, the crucial regulator of angiogenesis, lymphangiogenesis, lipid metabolism and inflammation, is involved in the development of atherosclerosis and further CVDs (cardiovascular diseases). This review discusses the general regulation and functions of VEGFs, their role in lipid metabolism and atherosclerosis development and progression. These functions present the great potential of applying the VEGF family as a target in the treatment of atherosclerosis and related CVDs. In addition, we discuss several modern anti-atherosclerosis VEGFs-targeted experimental procedures, drugs and natural compounds, which could significantly improve the efficiency of atherosclerosis and related CVDs’ treatment. |
| نوع الوثيقة: |
text |
| وصف الملف: |
application/pdf |
| اللغة: |
English |
| Relation: |
Biochemistry; https://dx.doi.org/10.3390/ijms23020931 |
| DOI: |
10.3390/ijms23020931 |
| الاتاحة: |
https://doi.org/10.3390/ijms23020931 |
| Rights: |
https://creativecommons.org/licenses/by/4.0/ |
| رقم الانضمام: |
edsbas.55DA7090 |
| قاعدة البيانات: |
BASE |