Academic Journal
A vaccinology approach to the identification and characterization of Dermanyssus gallinae candidate protective antigens for the control of poultry red mite infestations
| العنوان: | A vaccinology approach to the identification and characterization of Dermanyssus gallinae candidate protective antigens for the control of poultry red mite infestations |
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| المؤلفون: | Lima-Barbero, José Francisco, Contreras, Marinela, Mateos-Hernández, Lourdes, Mata-Lorenzo, Francisco Manuel, Triguero-Ocaña, Roxana, Sparagano, Olivier, Finn, Robert D., Strube, Christina, Price, Daniel R. G., Nunn, Francesca, Bartley, Kathryn, Höfle, Ursula, Boadella, Mariana, Nisbet, Alasdair J., Fuente, José de la, Villar, Margarita, de la Fuente, José |
| سنة النشر: | 2019 |
| مصطلحات موضوعية: | article, Verzeichnis wissenschaftlicher Veröffentlichungen, ddc:630, Hochschulbibliographie allgemein, Vaccine, Control, Proteomics, protective antigens, Dermanyssus, Vaccinology, Poultry Red Mite |
| Time: | 2019 |
| الوصف: | The poultry red mite (PRM), Dermanyssus gallinae, is a hematophagous ectoparasite considered as the major pest in the egg-laying industry. Its pesticide-based control is only partially successful and requires the development of new control interventions such as vaccines. In this study, we follow a vaccinology approach to identify PRM candidate protective antigens. Based on proteomic data from fed and unfed nymph and adult mites, we selected a novel PRM protein, calumenin (Deg-CALU), which is tested as a vaccine candidate on an on-hen trial. Rhipicephalus microplus Subolesin (Rhm-SUB) was chosen as a positive control. Deg-CALU and Rhm-SUB reduced the mite oviposition by 35 and 44%, respectively. These results support Deg-CALU and Rhm-SUB as candidate protective antigens for the PRM control. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | Vaccines -- https://www.mdpi.com/journal/vaccines -- http://www.bibliothek.uni-regensburg.de/ezeit/?2703319 -- 2703319-3 -- 2076-393X; https://doi.org/10.3390/vaccines7040190; https://elib.tiho-hannover.de/receive/tiho_mods_00001758; https://elib.tiho-hannover.de/servlets/MCRFileNodeServlet/tiho_derivate_00000450/vaccines-07-00190-v2.pdf; https://europepmc.org/articles/PMC6963798; https://www.mdpi.com/2076-393X/7/4/190 |
| DOI: | 10.3390/vaccines7040190 |
| الاتاحة: | https://doi.org/10.3390/vaccines7040190 https://elib.tiho-hannover.de/receive/tiho_mods_00001758 https://elib.tiho-hannover.de/servlets/MCRFileNodeServlet/tiho_derivate_00000450/vaccines-07-00190-v2.pdf https://europepmc.org/articles/PMC6963798 https://www.mdpi.com/2076-393X/7/4/190 |
| Rights: | https://creativecommons.org/licenses/by/4.0/ ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.551BD93C |
| قاعدة البيانات: | BASE |
| DOI: | 10.3390/vaccines7040190 |
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