Supplementary_material.docx

التفاصيل البيبلوغرافية
العنوان:	Supplementary_material.docx
المؤلفون:	Junpei Kawamura
سنة النشر:	2023
مصطلحات موضوعية:	Cardiology (incl. cardiovascular diseases), cyanotic CHD, Glenn procedure, PAVM, miR-25-3p, PHLPP2
الوصف:	・We novelty identified a circulating microRNA, miR-25-3p, in patients with acquired pulmonary arteriovenous malformations (PAVMs) post-Glenn procedure. ・We validated the roles of miR-25-3p and its target PHLPP2 (PH domain and leucine-rich repeat protein phosphatase 2) in human lung microvascular endothelial cell angiogenesis. ・Downregulation of PHLPP2 upregulates the endogenous HIF-1α/VEGF/VEGFR axis in lung microvascular endothelial cells under hypoxic conditions, resulting in abnormal angiogenesis in patients with PAVMs after Glenn procedure.
نوع الوثيقة:	text
اللغة:	unknown
Relation:	https://figshare.com/articles/online_resource/Supplementary_material_docx/24559363
DOI:	10.6084/m9.figshare.24559363.v1
الاتاحة:	https://doi.org/10.6084/m9.figshare.24559363.v1 https://figshare.com/articles/online_resource/Supplementary_material_docx/24559363
Rights:	CC BY 4.0
رقم الانضمام:	edsbas.54BA9CD8
قاعدة البيانات:	BASE

الوصف
DOI:	10.6084/m9.figshare.24559363.v1