Academic Journal
Management of Primary Immune Thrombocytopenia: Turkish Modified Delphi-Based Consensus Statement for Special Considerations
| العنوان: | Management of Primary Immune Thrombocytopenia: Turkish Modified Delphi-Based Consensus Statement for Special Considerations |
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| المؤلفون: | Calis, Umran, YAVAŞOĞLU, İRFAN, TOPTAŞ, TAYFUR, TOPRAK, SELAMİ KOÇAK, ŞAHİN, FULYA, SÖNMEZ, MEHMET, SAYINALP, NİLGÜN, ÖZKALEMKAŞ, FAHİR, KAYA, EMİN, Karakus, Volkan, Ayli, Meltem, Ayer, Mesut, AR, MUHLİS CEM, DEMİR, AHMET MUZAFFER, ÜMİT, ELİF GÜLSÜM |
| سنة النشر: | 2024 |
| الوصف: | Objective: Primary immune thrombocytopenia (ITP) is an acquired disorder of platelets with a complex and unclear mechanism of increased immune destruction or impaired production of platelets. While the management of ITP is evolving, there is still a need for guidance, particularly in certain circumstances such as pregnancy, emergencies, or patients requiring co-medications. We aimed to determine the tendencies of hematologists in T & uuml;rkiye in the event of such special considerations. Materials and Methods: Applying a modified Delphi method, the Turkish National ITP Working Group, founded under the auspices of the Turkish Society of Hematology, developed a questionnaire consisting of statements regarding pregnancy, emergencies, and circumstances requiring co-treatment with antiaggregants or anticoagulants. A total of 107 hematologists working in university or state hospitals voted for their agreement or disagreement with the statements for two sequential rounds. Results: The participating hematologists reached an agreement on starting treatment for pregnant patients with platelets of less than 30x109/L 9 /L and delivery either vaginally or by cesarean section being safe at platelet counts above 50x109/L. 9 /L. For emergencies and the rescue management of ITP, the panel agreed against the use of high-dose corticosteroids alone, preferring combinations with transfusions or intravenous immunoglobulin. For patients who require interventions, platelet counts of >50x109/L 9 /L were regarded as safe for low-risk procedures as well as co-treatment with antiplatelets or anticoagulants. Conclusion: As the National ITP Study Group, we have observed the need to increase the practice guidance regarding patients with primary ITP requiring additional treatments including invasive interventions and co-treatments for coagulation. Decisions on the management of ITP during pregnancy should be individualized. There is a lack of consensus on the thresholds of platelet counts as well as co-morbidities and co-medications. ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.4274/tjh.galenos.2024.2024.0101 |
| الاتاحة: | https://doi.org/10.4274/tjh.galenos.2024.2024.0101 https://avesis.hacettepe.edu.tr/publication/details/fc220520-25ac-4fc2-b900-4673926d8b6e/oai |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.548561B |
| قاعدة البيانات: | BASE |
| DOI: | 10.4274/tjh.galenos.2024.2024.0101 |
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