Academic Journal
Thyrotoxicosis presenting as hypokalaemic paralysis and hyperlactataemia in an oriental man
| العنوان: | Thyrotoxicosis presenting as hypokalaemic paralysis and hyperlactataemia in an oriental man |
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| المؤلفون: | Al-Jubouri, M A, Inkster, G D, Nee, P A, Andrews, F J |
| المصدر: | Annals of Clinical Biochemistry: International Journal of Laboratory Medicine ; volume 43, issue 4, page 323-325 ; ISSN 0004-5632 1758-1001 |
| بيانات النشر: | SAGE Publications |
| سنة النشر: | 2006 |
| الوصف: | A 35-year-old Malaysian man presented with rapid onset of flaccid quadriparesis associated with nausea and vomiting. General blood tests revealed severe hypokalaemia (serum potassium 1.5 mmol/L) and hypophosphataemia (serum phosphate 0.29 mmol/L) as a potential cause of the flaccid paralysis. Arterial blood gases showed mixed acid base disturbance of respiratory alkalosis and metabolic acidosis with hyperlactataemia. Thyrotoxic periodic paralysis (TPP) was suspected as the underlying cause of this presentation and thyroid function tests showed severe hyperthyroid results (free T4 > 77.2 pmol/L, free T3 19.3 pmol/L, thyroid-stimulating hormone [TSH] < 0.05 mIU/L). Treatment with intravenous potassium and phosphate infusion and oral propranolol resulted in rapid resolution of his symptoms. A discussion of the clinical and pathophysiological features and treatment of TPP (a very rare encounter in UK clinical practice) is presented, and to our knowledge associated hyperlactataemia has not been previously described. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| DOI: | 10.1258/000456306777695681 |
| الاتاحة: | https://doi.org/10.1258/000456306777695681 https://journals.sagepub.com/doi/pdf/10.1258/000456306777695681 |
| Rights: | https://journals.sagepub.com/page/policies/text-and-data-mining-license |
| رقم الانضمام: | edsbas.542D2392 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1258/000456306777695681 |
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