التفاصيل البيبلوغرافية
| العنوان: |
Effect of processing and nebulization on hLYS aggregation. |
| المؤلفون: |
Ashlee D. Brunaugh (4263472), Hyojong Seo (10131206), Zachary Warnken (10131209), Li Ding (16240), Sang Heui Seo (10131212), Hugh D. C. Smyth (7309253) |
| سنة النشر: |
2021 |
| المجموعة: |
Smithsonian Institution: Digital Repository |
| مصطلحات موضوعية: |
Biochemistry, Medicine, Microbiology, Molecular Biology, Pharmacology, Biotechnology, Cancer, Infectious Diseases, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, COVID -19, hLYS, drug levels, development approach, sequalae Niclosamide, powder inhaler, methicillin-resistance staphylococc., coronavirus strains, SARS-CoV -2 infections, coronavirus infections, COVID -19 pandemic, SARS-CoV -2, wide-spread utilization, formulation results, novel formulation, niclosamide-lysozyme particles, SARS-CoV -2 acquisition, vivo activity |
| الوصف: |
Spray drying (B) did not result in additional formation of soluble aggregates compared to the unprocessed control (A). NIC-hLYS reconstituted at a concentration of 25 mg/mL (C), 50 mg/mL (D), 75 mg/mL (E), and 100 mg/mL (F) was nebulized over the course of 2 minutes from an Aerogen Solo® vibrating mesh nebulizer. This process did not result in additional aggregation compared to the unprocessed control. (DOCX) |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/journal_contribution/Effect_of_processing_and_nebulization_on_hLYS_aggregation_/13918118 |
| DOI: |
10.1371/journal.pone.0246803.s005 |
| الاتاحة: |
https://doi.org/10.1371/journal.pone.0246803.s005 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.54211B08 |
| قاعدة البيانات: |
BASE |