Academic Journal
Target highlights in CASP14: analysis of models by structure providers
| العنوان: | Target highlights in CASP14: analysis of models by structure providers |
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| المؤلفون: | Alexander, Leila T., Lepore, Rosalba, Kryshtafovych, Andriy, Adamopoulos, Athanassios, Alahuhta, Markus, Arvin, Ann M., Bomble, Yannick J., Böttcher, Bettina, Breyton, Cécile, Chiarini, Valerio, Chinnam, Naga Babu, Chiu, Wah, Fidelis, Krzysztof, Grinter, Rhys, Gupta, Gagan D., Hartmann, Marcus D., Hayes, Christopher S., Heidebrecht, Tatjana, Ilari, Andrea, Joachimiak, Andrzej, Kim, Youngchang, Linares, Romain, Lovering, Andrew L., Lunin, Vladimir V., Lupas, Andrei N., Makbul, Cihan, Michalska, Karolina, Moult, John, Mukherjee, Prasun K., Nutt, William Sam, Oliver, Stefan L., Perrakis, Anastassis, Stols, Lucy, Tainer, John A., Topf, Maya, Tsutakawa, Susan E., Valdivia-Delgado, Mauricio, Schwede, Torsten |
| بيانات النشر: | Wiley-Blackwell |
| سنة النشر: | 2021 |
| المجموعة: | University of Basel: edoc |
| الوصف: | The biological and functional significance of selected CASP14 targets are described by the authors of the structures. The authors highlight the most relevant features of the target proteins and discuss how well these features were reproduced in the respective submitted predictions. The overall ability to predict three-dimensional structures of proteins has improved remarkably in CASP14, and many difficult targets were modelled with impressive accuracy. For the first time in the history of CASP, the experimentalists not only highlighted that computational models can accurately reproduce the most critical structural features observed in their targets, but also envisaged that models could serve as a guidance for further studies of biologically-relevant properties of proteins. This article is protected by copyright. All rights reserved. |
| نوع الوثيقة: | article in journal/newspaper |
| وصف الملف: | application/pdf |
| اللغة: | English |
| تدمد: | 0887-3585 1097-0134 |
| Relation: | https://edoc.unibas.ch/84743/1/prot.26247%20%281%29.pdf; Alexander, Leila T. and Lepore, Rosalba and Kryshtafovych, Andriy and Adamopoulos, Athanassios and Alahuhta, Markus and Arvin, Ann M. and Bomble, Yannick J. and Böttcher, Bettina and Breyton, Cécile and Chiarini, Valerio and Chinnam, Naga Babu and Chiu, Wah and Fidelis, Krzysztof and Grinter, Rhys and Gupta, Gagan D. and Hartmann, Marcus D. and Hayes, Christopher S. and Heidebrecht, Tatjana and Ilari, Andrea and Joachimiak, Andrzej and Kim, Youngchang and Linares, Romain and Lovering, Andrew L. and Lunin, Vladimir V. and Lupas, Andrei N. and Makbul, Cihan and Michalska, Karolina and Moult, John and Mukherjee, Prasun K. and Nutt, William Sam and Oliver, Stefan L. and Perrakis, Anastassis and Stols, Lucy and Tainer, John A. and Topf, Maya and Tsutakawa, Susan E. and Valdivia-Delgado, Mauricio and Schwede, Torsten. (2021) Target highlights in CASP14: analysis of models by structure providers. Proteins: Structure, Function, and Bioinformatics . pp. 1-26.; info:pmid/34561912; urn:ISSN:0887-3585; urn:ISSN:1097-0134 |
| DOI: | 10.1002/prot.26247 |
| الاتاحة: | https://edoc.unibas.ch/84743/ https://edoc.unibas.ch/84743/1/prot.26247%20%281%29.pdf https://doi.org/10.1002/prot.26247 |
| Rights: | cc_by ; info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.5369AB87 |
| قاعدة البيانات: | BASE |
| تدمد: | 08873585 10970134 |
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| DOI: | 10.1002/prot.26247 |