The Tribulations of Trials: Lessons Learnt Recruiting 777 Older Adults into REtirement in ACTion (REACT), a Trial of a Community, Group-Based Active Aging Intervention Targeting Mobility Disability

التفاصيل البيبلوغرافية
العنوان:	The Tribulations of Trials: Lessons Learnt Recruiting 777 Older Adults into REtirement in ACTion (REACT), a Trial of a Community, Group-Based Active Aging Intervention Targeting Mobility Disability
المؤلفون:	Withall J., Greaves C.J., Thompson J.L., De Koning J.L., Bollen J.C., Moorlock S.J., Fox K.R., Western M.J., Snowsill T., Medina-Lara A., Cross R., Ladlow P., Taylor G., Zisi V., Clynes J., Gray S., Agyapong-Badu S., Guralnik J.M., Rejeski W.J., Stathi A.
المصدر:	Journals of Gerontology - Series A Biological Sciences and Medical Sciences ; https://www.scopus.com/inward/record.uri?eid=2-s2.0-85096151742&doi=10.1093%2fgerona%2fglaa051&partnerID=40&md5=d4bee7135dd607933f8bdb2c501c0713
سنة النشر:	2020
المجموعة:	University of Thessaly Institutional Repository / Ιδρυματικό Αποθετήριο Πανεπιστημίου Θεσσαλίας
مصطلحات موضوعية:	aged, clinical trial, controlled study, disabled person, female, healthy aging, human, independent living, male, multicenter study, patient selection, randomized controlled trial, rehabilitation, retirement, United Kingdom, walking difficulty, Disabled Persons, Humans, Mobility Limitation, Oxford University Press
الوصف:	Background: Challenges of recruitment to randomized controlled trials (RCTs) and successful strategies to overcome them should be clearly reported to improve recruitment into future trials. REtirement in ACTion (REACT) is a United Kingdom-based multicenter RCT recruiting older adults at high risk of mobility disability to a 12-month group-based exercise and behavior maintenance program or to a minimal Healthy Aging control intervention. Methods: The recruitment target was 768 adults, aged 65 years and older scoring 4-9 on the Short Physical Performance Battery (SPPB). Recruitment methods include the following: (a) invitations mailed by general practitioners (GPs); (b) invitations distributed via third-sector organizations; and (c) public relations (PR) campaign. Yields, efficiency, and costs were calculated. Results: The study recruited 777 (33.9% men) community-dwelling, older adults (mean age 77.55 years (SD 6.79), mean SPPB score 7.37 (SD 1.56)), 95.11% white (n = 739) and broadly representative of UK quintiles of deprivation. Over a 20-month recruitment period, 25,559 invitations were issued. Eighty-eight percent of the participants were recruited via GP invitations, 5.4% via the PR campaign, 3% via word-of-mouth, and 2.5% via third-sector organizations. Mean recruitment cost per participant was £78.47, with an extra £26.54 per recruit paid to GPs to cover research costs. Conclusions: REACT successfully recruited to target. Response rates were lower than initially predicted and recruitment timescales required adjustment. Written invitations from GPs were the most efficient method for recruiting older adults at risk of mobility disability. Targeted efforts could achieve more ethnically diverse cohorts. All trials should be required to provide recruitment data to enable evidence-based planning of future trials. © 2020 The Author(s) 2020. Published by Oxford University Press on behalf of The Gerontological Society of America.
نوع الوثيقة:	article in journal/newspaper
اللغة:	English
تدمد:	10795006
Relation:	http://hdl.handle.net/11615/80802
DOI:	10.1093/gerona/glaa051
الاتاحة:	http://hdl.handle.net/11615/80802 https://doi.org/10.1093/gerona/glaa051
رقم الانضمام:	edsbas.51750502
قاعدة البيانات:	BASE

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الوصف
تدمد:	10795006
DOI:	10.1093/gerona/glaa051