Coronary vasoconstricting responses to serotonin before and after hydroxyfasudil.

التفاصيل البيبلوغرافية
العنوان: Coronary vasoconstricting responses to serotonin before and after hydroxyfasudil.
المؤلفون: Tasuku Watanabe (6954716), Yasuharu Matsumoto (107815), Kensuke Nishimiya (612853), Tomohiko Shindo (612852), Hirokazu Amamizu (11426470), Jun Sugisawa (11426473), Satoshi Tsuchiya (1973818), Koichi Sato (207269), Susumu Morosawa (11426476), Kazuma Ohyama (11426479), Tomomi Watanabe-Asaka (802268), Moyuru Hayashi (3628421), Yoshiko Kawai (11426482), Jun Takahashi (464660), Satoshi Yasuda (164326), Hiroaki Shimokawa (381195)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Medicine, Cell Biology, Ecology, Immunology, Developmental Biology, Cancer, Infectious Diseases, safe therapeutic approach, left anterior descending, intensity pulsed ultrasound, ameliorates myocardial ischemia, 3 different levels, performed coronary angiography, coronary adventitial inflammation, lymph transport speed, sham therapy groups, lipus group compared, invasive lipus therapy, des edges showed, sham therapy group, coronary stent implantation, vivo , sham group, coronary artery, lipus group, des implantation, des edges, enhanced lymph, stent implantation, stent edges
الوصف: Representative CAG at 4 weeks ( A , D ) after intracoronary nitroglycerin (10 μg/kg), ( B , E ) serotonin (100 μg/kg), and ( C , F ) serotonin after pre-treatment with hydroxyfasudil (a selective Rho-kinase inhibitor, 300 μg/kg). Coronary hyperconstricting responses at the stent edges (blue and red arrows) of EES (yellow lines) were markedly suppressed in the LIPUS group compared with the sham group ( B, E ), which were fully abolished by hydroxyfasudil ( C, F ). ( G ) Coronary vasoconstriction to serotonin was significantly attenuated in the LIPUS group compared with the sham group, which was prevented by hydroxyfasudil. ( H ) Vasoconstriction was not evident in the control arteries. Results are expressed as mean±SEM. SEM = standard error of mean; other abbreviations as in Fig 1 .
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Coronary_vasoconstricting_responses_to_serotonin_before_and_after_hydroxyfasudil_/16612222
DOI: 10.1371/journal.pone.0257175.g002
الاتاحة: https://doi.org/10.1371/journal.pone.0257175.g002
Rights: CC BY 4.0
رقم الانضمام: edsbas.514C629A
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pone.0257175.g002