Academic Journal
Treatment of first tonic-clonic seizure does not affect mortality: long-term follow-up of a randomised clinical trial
| العنوان: | Treatment of first tonic-clonic seizure does not affect mortality: long-term follow-up of a randomised clinical trial |
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| المؤلفون: | Leone , Ma, Vallalta , R, Solari , A, Beghi , E, First , Group, Mazza, Salvatore |
| المساهمون: | Leone, Ma, Vallalta, R, Solari, A, Beghi, E, First, Group, Mazza, Salvatore |
| بيانات النشر: | BMJ Publishing Group GBR |
| سنة النشر: | 2011 |
| المجموعة: | Università Cattolica del Sacro Cuore: PubliCatt |
| مصطلحات موضوعية: | first tonic-clonic seizure, treatment, mortality, Settore MED/26 - NEUROLOGIA |
| الوصف: | 1. J Neurol Neurosurg Psychiatry. 2011 Aug;82(8):924-7. Epub 2011 Apr 28. Treatment of first tonic-clonic seizure does not affect mortality: long-term follow-up of a randomised clinical trial. Leone MA, Vallalta R, Solari A, Beghi E; FIRST Group. Collaborators: Hauser WA, Fratiglioni L, Bogliun G, Del Felice A, Aloisi P, Marelli A, Porto C, Fusi L, Francesconi C, Gambaro P, Basso P, Freschi R, Meregalli S, Boati E, Mamoli A, Gavalotti B, Camerlingo M, Rottoli MR, Bottacchi E, Carenini L, Sironi L, Casara GL, Vecchi M, Covezzi E, Tortorici G, Franzoni E, Marchiani V, Moscano F, Giuliani G, Angeleri VA, Polonara S, Terziani S, Quattrini A, Ortenzi A, Paggi A, Iemolo F, Geda C, Ferrari GF, Binetti MA, Martini A, Perenchio MT, Malvezzi L, Tabladon G, Severi S, Zolo P, Montano V, Fassio F, Vignolo L, Pasolini MP, Antonini L, De Maria G, Rossi G, Tonini C, Cittani D, Zagnoni PG, Clerici D, Romeo A, Viri M, Lodi M, Mazza S, Vaccario ML, De Mattei M, Cremo R, Zaina P, Gentile S, Lovera N, Piazza D, Ravetti C, Cavestro C, Rosettani P. SCDU Neurologia, AOU Maggiore della Carità, C.so Mazzini 18, 28100 Novara, Italy. maurizio.leone@maggioreosp.novara.it Comment in J Neurol Neurosurg Psychiatry. 2011 Aug;82(8):829. BACKGROUND: Information on the effects of early treatment of seizures on mortality is scarce. The authors assessed the survival of patients with a first generalised tonic-clonic seizure, randomised to immediate treatment (treated) versus treatment only in the event of seizure recurrence (untreated), over a 20-year period. METHODS: The authors followed 419 patients. The median follow-up was 19.7 years (range 0.2-21.5) for a total of 7867 person-years. RESULTS: 40 persons (9.6%) died during follow-up, 19 (8.9%) treated and 21 (10.3.%) untreated. The probability of surviving was 100% at 1 year, 97% (95% CI 95% to 99%) at 5 years, 94% (91-97) at 10 years and 91% (87-95) at 20 years in treated patients and 100%, 98% (95-100), 97% (94-99) and 89% (85-94), respectively, in untreated patients (p=0.7). After adjustment ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| Relation: | info:eu-repo/semantics/altIdentifier/pmid/21531706; volume:82; issue:8; firstpage:924; lastpage:927; numberofpages:4; issueyear:2011; journal:JOURNAL OF NEUROLOGY, NEUROSURGERY AND PSYCHIATRY; http://hdl.handle.net/10807/3041 |
| الاتاحة: | http://hdl.handle.net/10807/3041 |
| رقم الانضمام: | edsbas.5123B1BE |
| قاعدة البيانات: | BASE |
| الوصف غير متاح. |