Academic Journal
Anti-cyclic citrullinated peptide antibodies – a role in rheumatoid arthritis and the possibility of seroconversion: A focus on abatacept
| العنوان: | Anti-cyclic citrullinated peptide antibodies – a role in rheumatoid arthritis and the possibility of seroconversion: A focus on abatacept |
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| المؤلفون: | N. V. Chichasova |
| المصدر: | Современная ревматология, Vol 11, Iss 1, Pp 79-86 (2017) |
| بيانات النشر: | IMA-PRESS LLC |
| سنة النشر: | 2017 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | серопозитивность, сероконверсия, антитела к циклическому цитруллинированному пептиду, ревматоидный артрит, ревматоидный фактор, абатацепт, Medicine |
| الوصف: | The detection of anti-cyclic citrullinated peptide (anti-CCP) antibodies plays a diagnostic and statistical predictive role in rheumatoid arthritis (RA). The decreased concentration of anti-CCP antibodies or their seroconversion is observed for not all groups of anti-inflammatory drugs. Seropositivity for anti-CCP antibodies is a predictor of the higher efficacy of abatacept (ABC). The possibility of seroconversion of anti-CCP antibodies, like rheumatoid factor, during treatment with ABC is associated with the more pronounced suppression of clinical symptoms of RA activity and progressive joint destruction, with remission achievement in a large proportion of patients. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | Russian |
| تدمد: | 1996-7012 2310-158X |
| Relation: | https://mrj.ima-press.net/mrj/article/view/743; https://doaj.org/toc/1996-7012; https://doaj.org/toc/2310-158X; https://doaj.org/article/01a76c0801134a158581734baa044f42 |
| DOI: | 10.14412/1996-7012-2017-1-79-86 |
| الاتاحة: | https://doi.org/10.14412/1996-7012-2017-1-79-86 https://doaj.org/article/01a76c0801134a158581734baa044f42 |
| رقم الانضمام: | edsbas.51045607 |
| قاعدة البيانات: | BASE |
| تدمد: | 19967012 2310158X |
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| DOI: | 10.14412/1996-7012-2017-1-79-86 |