Conference
The impact of COVID-19 on quality of life among patients with inflammatory bowel diseases – A Danish prospective population-based cohort study
| العنوان: | The impact of COVID-19 on quality of life among patients with inflammatory bowel diseases – A Danish prospective population-based cohort study |
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| المؤلفون: | Attauabi, M, Dahlerup, J F, Poulsen, A, Hansen, M R, Vester-Andersen, M K, Eraslan, S, Prahm, A P, Pedersen, N, Larsen, L, Jess, T, Neumann, A, Haderslev, K V, Molazahi, A, Lødrup, A B, Glerup, H, Oppfeldt, A M, Jensen, M D, Theede, K, Kiszka-Kanowitz, M, Seidelin, J B, Burisch, J |
| المصدر: | Attauabi , M , Dahlerup , J F , Poulsen , A , Hansen , M R , Vester-Andersen , M K , Eraslan , S , Prahm , A P , Pedersen , N , Larsen , L , Jess , T , Neumann , A , Haderslev , K V , Molazahi , A , Lødrup , A B , Glerup , H , Oppfeldt , A M , Jensen , M D , Theede , K , Kiszka-Kanowitz , M , Seidelin , J B & Burisch , J 2022 , ' The impact of COVID-19 .... |
| سنة النشر: | 2022 |
| المجموعة: | University of Southern Denmark: Research Output / Syddansk Universitet |
| الوصف: | Background The coronavirus disease 2019 (COVID-19) pandemic raised concerns among patients with ulcerative colitis (UC) and Crohn’s disease (CD) fearing an increased susceptibility to infection and increased risk of poor outcomes. Furthermore, the impact of COVID-19 on subsequent health-related quality of life (HRQoL) has so far not been described. We aimed to evaluate the HRQoL in relation to the severity of COVID-19 in a cohort of survivors. Methods We conducted a population-based study investigating the outcomes of COVID-19 among patients with UC and CD in Denmark. The Danish COVID-19 IBD Database is an extensive population-based database which prospectively monitors the disease course of laboratory-confirmed COVID-19 among patients with UC and CD. Severe COVID-19 was defined as COVID-19 necessitating intensive care unit admission, ventilator use, or death, while adverse COVID-19 was defined as requirement of COVID-19 related hospitalization. HRQoL was assessed using several validated questionnaires, including the EuroQol five-dimension five-level (EQ-5D-5L) questionnaire, EuroQol Visual Analogue Scale (EQ-VAS), Short Inflammatory Bowel Disease Questionnaire (SIBDQ), IBD Disability Index (IBD-DI), and IBD Fatigue Score. Results HRQoL after COVID-19 was assessed among 137/319 (42.9%) patients with UC of whom 125 (91.2%) and 12 (8.8%) patients experienced mild and adverse COVID-19, respectively. Furthermore, HRQoL was assessed among 85/197 (43.1%) patients with CD of whom 74 (87.1%) and 11 (12.9%) patients experienced mild and adverse COVID-19, respectively. HRQoL was assessed after a median of 5.1 months (IQR 4.5–7.9) after infection. Baseline characteristics are presented according to the availability of HRQoL data in Table 1. No difference was observed in terms of EQ-5D-5L among patients with UC and CD or patients with mild, adverse, or severe COVID-19 (Table 2). Accordingly, the SIBDQ scores were similar among patients with mild, adverse or severe COVID-19 and UC (mild: median 59 (IQR 50–65), ... |
| نوع الوثيقة: | conference object |
| اللغة: | English |
| Relation: | https://portal.findresearcher.sdu.dk/da/publications/01d47ee4-9c64-4a81-a4c7-4b2a6406696c |
| DOI: | 10.1093/ecco-jcc/jjab232.771 |
| الاتاحة: | https://portal.findresearcher.sdu.dk/da/publications/01d47ee4-9c64-4a81-a4c7-4b2a6406696c https://doi.org/10.1093/ecco-jcc/jjab232.771 |
| Rights: | info:eu-repo/semantics/openAccess |
| رقم الانضمام: | edsbas.50943C8 |
| قاعدة البيانات: | BASE |
| DOI: | 10.1093/ecco-jcc/jjab232.771 |
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