التفاصيل البيبلوغرافية
| العنوان: |
Marc1 gene deletion has no effect on circulating or liver lipids in male mice fed choline-deficient L-amino acid defined high fat diet (CDAA-HFD). |
| المؤلفون: |
Eriks Smagris, Lisa M. Shihanian, Ivory J. Mintah, Parnian Bigdelou, Yuliya Livson, Heather Brown, Niek Verweij, Charleen Hunt, Reid O’Brien Johnson, Tyler J. Greer, Suzanne A. Hartford, George Hindy, Luanluan Sun, Jonas B. Nielsen, Gabor Halasz, Luca A. Lotta, Andrew J. Murphy, Mark W. Sleeman, Viktoria Gusarova |
| سنة النشر: |
2024 |
| مصطلحات موضوعية: |
Biochemistry, Genetics, Cancer, Virology, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, five ancestry groups, lower hepatic fat, hepatic triglyceride accumulation, wide association study, wide association studies, div >< p, suggesting marc1 inhibition, recent human genome, deletion may lead, marc1 physiological function, mouse , marc1 <, hepatic cells, vitro studies, study found, function variants, >, marc1 plays, recapitulated earlier, phenotype similar, paralogue marc2, observed phenotype |
| الوصف: |
Nine weeks old male mice (11 WT and 10 Marc1 KO) were fed with CDAA-HFD for 18 weeks. (A) Body mass gain was measured every 2 weeks, (B) body composition (Micro CT) of mice were assessed at week 6 of experiment. (C) Serum, (D) liver lipids, (E) selected liver gene expression (mRNA by qRT-PCR) were performed at end of experiment. Each point represents individual mouse, mean ± s.e.m. are shown in all graphs, *p<0.05, ***p<0.001, ****p<0.0001. (TIF) |
| نوع الوثيقة: |
still image |
| اللغة: |
unknown |
| Relation: |
https://figshare.com/articles/figure/Marc1_gene_deletion_has_no_effect_on_circulating_or_liver_lipids_in_male_mice_fed_choline-deficient_L-amino_acid_defined_high_fat_diet_CDAA-HFD_/25337563 |
| DOI: |
10.1371/journal.pgen.1011179.s007 |
| الاتاحة: |
https://doi.org/10.1371/journal.pgen.1011179.s007
https://figshare.com/articles/figure/Marc1_gene_deletion_has_no_effect_on_circulating_or_liver_lipids_in_male_mice_fed_choline-deficient_L-amino_acid_defined_high_fat_diet_CDAA-HFD_/25337563 |
| Rights: |
CC BY 4.0 |
| رقم الانضمام: |
edsbas.4F868A50 |
| قاعدة البيانات: |
BASE |