Academic Journal

Genotyping of dengue virus from infected tissue samples embedded in paraffin

التفاصيل البيبلوغرافية
العنوان: Genotyping of dengue virus from infected tissue samples embedded in paraffin
المؤلفون: Rivera, Jorge Alonso, Rengifo, Aura Caterine, Rosales Munar, Alicia, Díaz Herrera, Taylor H., Usme Ciro, Jose A., Parra, Edgar, Álvarez Díaz, Diego Alejandro, Laiton Donato, Katherine, Caldas, Maria Leonor
المساهمون: CIST-Centro de Investigación en Salud para el Trópico
المصدر: https://virologyj.biomedcentral.com/articles/10.1186/s12985-023-02072-5.
بيانات النشر: Universidad Cooperativa de Colombia, Facultad de Ciencias de la Salud, Medicina, Santa Marta
Externo
سنة النشر: 2023
الوصف: Dengue has become one of the vector-borne diseases that affect humans worldwide. In Latin American countries, Colombia is historically one of the most affected by epidemics of this flavivirus. The underreporting of signs and symptoms of probable cases of dengue, the lack of characterization of the serotypes of the infection, and the few detailed studies of postmortem necropsies of patients are among other conditions that have delayed progress in the knowledge of the pathogenesis of the disease. This study presents the results of fragment sequencing assays on paraffin-embedded tissue samples from fatal DENV cases during the 2010 epidemic in Colombia. We found that the predominant serotype was DENV-2, with the Asian/American genotype of lineages 1 and 2. This work is one of the few reports of the circulating genotypes of dengue during the 2010 epidemic in Colombia, one of the most lethal dates in the country's history. ; Instituto Nacional de Salud
نوع الوثيقة: article in journal/newspaper
وصف الملف: 10 páginas; application/pdf
اللغة: English
تدمد: 1743-422X
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الاتاحة: https://hdl.handle.net/20.500.12494/55527
Rights: http://creativecommons.org/licenses/by-nc-nd/4.0/ ; Attribution-NonCommercial-NoDerivatives 4.0 International
رقم الانضمام: edsbas.4F6B3CA3
قاعدة البيانات: BASE