Academic Journal
An Easy Scalable Approach to HMF Employing DMC as Reaction Media: Reaction Optimization and Comparative Environmental Assessment
| العنوان: | An Easy Scalable Approach to HMF Employing DMC as Reaction Media: Reaction Optimization and Comparative Environmental Assessment |
|---|---|
| المؤلفون: | Musolino, Manuele, Andraos, John, Aricò, Fabio |
| المساهمون: | Musolino, Manuele, Andraos, John, Aricò, Fabio |
| سنة النشر: | 2018 |
| المجموعة: | Università Ca’ Foscari Venezia: ARCA (Archivio Istituzionale della Ricerca) |
| مصطلحات موضوعية: | Carboidrati, platform chemicals, HMF, Dialchil carbonati, Green Chemistry, Green metrics, Settore CHIM/06 - Chimica Organica |
| الوصف: | In this work, bio-based platform molecule 5-hydroxymethylfurfural (HMF) was synthesised under mild conditions (90 °C) from D-fructose using as media a mixture of dimethyl carbonate:tetraethyl ammonium bromide (DMC:TEAB). This solvent system resulted in a efficient production of HMF in the presence of both Amberlyst-15 (heterogeneous catalyst) and BF3O(Et)2 (homogeneous catalyst). HMF was recovered from the reaction mixture with or without minimal work-up. It is noteworthy that this synthetic approach provided high yielding product also when performed in a large-scale. Quick reduction of HMF to the related 2,5-bis(hydroxymethyl)furan was also conducted to further confirm the proposed procedure. Besides, the materials efficiency metrics of the optimized DMC-based synthetic approach have been compared to alternative syntheses for HMF reported in the literature. This latter study takes into consideration synthetic routes that employ D-fructose as substrate, easy accessible catalysts and report detailed procedures and evidence of the isolation of HMF. ; In this work, bio-based platform molecule 5-hydroxymethylfurfural (HMF) was synthesised under mild conditions (90 degrees C) from D-fructose using as media a mixture of dimethyl carbonate:tetraethyl ammonium bromide (DMC:TEAB). This solvent system resulted in a efficient production of HMF in the presence of both Amberlyst-15 (heterogeneous catalyst) and BF3O(Et)(2) (homogeneous catalyst). HMF was recovered from the reaction mixture with or without minimal work-up. It is noteworthy that this synthetic approach provided high yielding product also when performed in a large-scale. Quick reduction of HMF to the related 2,5-bis(hydroxymethyl)furan was also conducted to further confirm the proposed procedure. Besides, the materials efficiency metrics of the optimized DMC-based synthetic approach have been compared to alternative syntheses for HMF reported in the literature. This latter study takes into consideration synthetic routes that employ D-fructose as substrate, easy ... |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | unknown |
| Relation: | info:eu-repo/semantics/altIdentifier/wos/WOS:000426495600023; volume:3; issue:8; firstpage:2359; lastpage:2365; numberofpages:7; journal:CHEMISTRYSELECT; http://hdl.handle.net/10278/3697836; info:eu-repo/semantics/altIdentifier/scopus/2-s2.0-85042641713 |
| DOI: | 10.1002/slct.201800198 |
| الاتاحة: | http://hdl.handle.net/10278/3697836 https://doi.org/10.1002/slct.201800198 |
| Rights: | info:eu-repo/semantics/closedAccess |
| رقم الانضمام: | edsbas.4F40FB6E |
| قاعدة البيانات: | BASE |
| DOI: | 10.1002/slct.201800198 |
|---|