Distribution of affected (candidate) driver genes of MSH3-related tumourigenesis across all nine adenomas.

التفاصيل البيبلوغرافية
العنوان: Distribution of affected (candidate) driver genes of MSH3-related tumourigenesis across all nine adenomas.
المؤلفون: Claudia Perne (8886344), Sophia Peters (4632115), Maria Cartolano (3165243), Sukanya Horpaopan (4632121), Christina Grimm (280266), Janine Altmüller (120887), Anna K. Sommer (11767832), Axel M. Hillmer (10208966), Holger Thiele (455371), Margarete Odenthal (180129), Gabriela Möslein (4504525), Ronja Adam (333161), Sugirthan Sivalingam (3720064), Jutta Kirfel (210681), Michal R. Schweiger (11767835), Martin Peifer (222202), Isabel Spier (4632118), Stefan Aretz (4632109)
سنة النشر: 2021
المجموعة: Smithsonian Institution: Digital Repository
مصطلحات موضوعية: Medicine, Cell Biology, Genetics, Molecular Biology, Cancer, Virology, Space Science, Environmental Sciences not elsewhere classified, Biological Sciences not elsewhere classified, Mathematical Sciences not elsewhere classified, Chemical Sciences not elsewhere classified, whole exome sequencing, repetitive sequence context, matched normal tissue, familial adenomatous polyposis, >- related tumourigenesis, >- driven pathway, >- associated polyposis, 21 – 42, early colorectal carcinogenesis, characterise mutational signatures, somatic genetic variation, single nucleotide variants, div >< p, colorectal adenomas caused, candidate driver genes, colorectal adenomas, driver genes, somatic variants, pathogenic somatic
الوصف: The most interesting genes ( Table 2 ) are highlighted in red, the remaining genes (see S1 Table ), are highlighted in blue. The upper bar chart illustrates the number of (interesting) genes mutated per adenoma. Dark red/blue: truncating variants; light red/blue: missense variants or in-frame indels.
نوع الوثيقة: still image
اللغة: unknown
Relation: https://figshare.com/articles/figure/Distribution_of_affected_candidate_driver_genes_of_MSH3-related_tumourigenesis_across_all_nine_adenomas_/17094923
DOI: 10.1371/journal.pone.0259185.g004
الاتاحة: https://doi.org/10.1371/journal.pone.0259185.g004
Rights: CC BY 4.0
رقم الانضمام: edsbas.4F2B4159
قاعدة البيانات: BASE
الوصف
DOI:10.1371/journal.pone.0259185.g004