التفاصيل البيبلوغرافية
| العنوان: |
Negative association between smoking and positive SARS-CoV-2 testing: results from a swiss outpatient sample population |
| المؤلفون: |
Vallarta Robledo, Juan Ramon, Bico Rosa Gamero Sandoval, Jose Luis, Baggio, Stéphanie, Salamun, Julien, Jacquerioz, Frédérique Aline, Spechbach, Hervé, Guessous, Idris |
| المصدر: |
ISSN: 2296-2565 ; Frontiers in public health, vol. 9 (2021) 731981. |
| سنة النشر: |
2021 |
| مصطلحات موضوعية: |
info:eu-repo/classification/ddc/613, COVID-19, SARS-CoV-2, Outpatient testing, Public health, Smoking, Adult, Female, Humans, Outpatients, Smoking / adverse effects, Switzerland / epidemiology, psy, demo |
| الوصف: |
To date, most of the evidence suggests that smoking is negatively associated with testing positive for SARS-CoV-2. However, evidence has several methodological limitations. Using an outpatient sample population, we analyzed the association of testing positive for SARS-CoV-2 and smoking considering comorbidities, socioeconomic and demographic factors. Baseline data were obtained from a cohort during the first wave of the pandemic in Geneva, Switzerland (March-April 2020). RT-PCR tests were carried out on individuals suspected of having SARS-CoV-2 according to the testing strategy at that time. Logistic regressions were performed to test the association of smoking and testing positive for SARS-CoV-2 and further adjusted for comorbidities, socioeconomic and demographic factors. The sample included 5,169 participants; 60% were women and the mean age was 41 years. The unadjusted OR for testing positive for SARS-CoV-2 was 0.46 (CI: 0.38-0.54). After adjustment for comorbidities, socioeconomic and demographic factors, smoking was still negatively associated with testing positive for SARS-CoV-2 (OR: 0.44; CI: 0.35-0.77). Women (OR: 0.79; CI: 0.69-0.91), higher postal income (OR: 0.97; CI: 0.95-0.99), having respiratory (OR: 0.68; CI: 0.55-0.84) and immunosuppressive disorders (OR: 0.63; CI: 0.44-0.88) also showed independent negative associations with a positive test for SARS-CoV-2. Smoking was negatively associated with a positive test for SARS-CoV-2 independently of comorbidities, socioeconomic and demographic factors. Since having respiratory or immunosuppressive conditions and being females and healthcare workers were similarly negatively associated with SARS-CoV-2 positive testing, we hypothesize that risk factor-related protective or testing behaviors could have induced a negative association with SARS-CoV-2. |
| نوع الوثيقة: |
article in journal/newspaper |
| اللغة: |
English |
| Relation: |
https://archive-ouverte.unige.ch/unige:162750 |
| الاتاحة: |
https://archive-ouverte.unige.ch/unige:162750 |
| Rights: |
undefined |
| رقم الانضمام: |
edsbas.4F13D446 |
| قاعدة البيانات: |
BASE |