Academic Journal
Evaluation of the BD Phoenix CPO Detect Test for detection of carbapenemase-producing Enterobacterales
| العنوان: | Evaluation of the BD Phoenix CPO Detect Test for detection of carbapenemase-producing Enterobacterales |
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| المؤلفون: | DÖNMEZ, LEVENT, ÖĞÜNÇ, MERAL DİLARA, YAZISIZ, HATİCE, Kuskucu, Mert A., Midilli, Kenan, KOYUNCU ÖZYURT, ÖZLEM, Cetinkaya, Ozgul, ÖZHAK, BETİL, ÖNGÜT, GÖZDE, TURHAN, ÖZGE |
| المساهمون: | Akdeniz Üniversitesi , Tıp Fakültesi , Temel Tıp Bilimleri Bölümü, 4314091 |
| سنة النشر: | 2023 |
| مصطلحات موضوعية: | Mikrobiyoloji, Yaşam Bilimleri (LIFE), Yaşam Bilimleri, Temel Bilimler |
| الوصف: | Plain language summaryEnterobacterales are a type of bacteria that usually live harmlessly in the gut of humans. However, if the bacteria get access to the bladder or bloodstream, they can cause infection. Carbapenemase-producing Enterobacterales (CPE) are a type of bacteria that can cause carbapenem antibiotic-resistant infections, a group of powerful antibiotics. The rapid spread of CPE will pose an increasing threat to public health and medical treatment practices; therefore, rapid detection of CPE is crucial. This study assessed the performance of the BD Phoenix CPO Detect Test for the detection of carbapenemase-producing Enterobacterales. The BD Phoenix CPO Detect Test offers both the detection of carbapenemase production and antimicrobial susceptibility testing simultaneously and can be clinically useful for determining possible treatment options. Aims: This study aimed to evaluate the performance of the BD Phoenix CPO Detect Test (BD Diagnostic Systems) for the detection and classification of carbapenemase-mediated carbapenem resistance. Methods: A total of 447 Enterobacterales strains were included in the study. All strains were tested with the BD Phoenix CPO Detect Test and the modified carbapenem inactivation method. Results: Carbapenemase production was detected in 157 of 159 carbapenemase producers, including 95.7% of class B and 99.2% of class D isolates using the BD Phoenix CPO Detect Test. BD Phoenix CPO Detect has a sensitivity of 98.7% and a specificity of 95.5% in detecting carbapenemase production. Conclusion: The classification of OXA-48 and class B carbapenemases, the most common carbapenemases circulating in Turkey, was highly accurate. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 1746-0913 |
| Relation: | FUTURE MICROBIOLOGY; KOYUNCU ÖZYURT Ö., Cetinkaya O., ÖZHAK B., ÖNGÜT G., TURHAN Ö., YAZISIZ H., DÖNMEZ L., Kuskucu M. A., Midilli K., ÖĞÜNÇ M. D., "Evaluation of the BD Phoenix CPO Detect Test for detection of carbapenemase-producing Enterobacterales", FUTURE MICROBIOLOGY, sa.7, ss.399-405, 2023; vv_1032021; av_2177f1a1-72f0-4f78-b3d0-dcbc3c531099; http://hdl.handle.net/20.500.12627/190114; https://doi.org/10.2217/fmb-2022-0071; 399; 405 |
| DOI: | 10.2217/fmb-2022-0071 |
| الاتاحة: | https://hdl.handle.net/20.500.12627/190114 https://doi.org/10.2217/fmb-2022-0071 |
| رقم الانضمام: | edsbas.4E14579C |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 17460913 |
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| DOI: | 10.2217/fmb-2022-0071 |