Academic Journal
Chondrogenic Differentiation of Human Adipose-Derived Stem Cells: A New Path in Articular Cartilage Defect Management?
| العنوان: | Chondrogenic Differentiation of Human Adipose-Derived Stem Cells: A New Path in Articular Cartilage Defect Management? |
|---|---|
| المؤلفون: | Jan-Philipp Stromps, Nora Emilie Paul, Björn Rath, Mahtab Nourbakhsh, Jürgen Bernhagen, Norbert Pallua |
| المصدر: | BioMed Research International, Vol 2014 (2014) |
| بيانات النشر: | Hindawi Limited |
| سنة النشر: | 2014 |
| المجموعة: | Directory of Open Access Journals: DOAJ Articles |
| مصطلحات موضوعية: | Medicine |
| الوصف: | According to data published by the Centers for Disease Control and Prevention, over 6 million people undergo a variety of medical procedures for the repair of articular cartilage defects in the U.S. each year. Trauma, tumor, and age-related degeneration can cause major defects in articular cartilage, which has a poor intrinsic capacity for healing. Therefore, there is substantial interest in the development of novel cartilage tissue engineering strategies to restore articular cartilage defects to a normal or prediseased state. Special attention has been paid to the expansion of chondrocytes, which produce and maintain the cartilaginous matrix in healthy cartilage. This review summarizes the current efforts to generate chondrocytes from adipose-derived stem cells (ASCs) and provides an outlook on promising future strategies. |
| نوع الوثيقة: | article in journal/newspaper |
| اللغة: | English |
| تدمد: | 2314-6133 2314-6141 |
| Relation: | http://dx.doi.org/10.1155/2014/740926; https://doaj.org/toc/2314-6133; https://doaj.org/toc/2314-6141; https://doaj.org/article/547ca8155df14b1e991b75ca09ecfe3a |
| DOI: | 10.1155/2014/740926 |
| الاتاحة: | https://doi.org/10.1155/2014/740926 https://doaj.org/article/547ca8155df14b1e991b75ca09ecfe3a |
| رقم الانضمام: | edsbas.4E11E77E |
| قاعدة البيانات: | BASE |
Full Text Finder | تدمد: | 23146133 23146141 |
|---|---|
| DOI: | 10.1155/2014/740926 |